do whatever that special flag was supposed to do. So essentially, without this, we would have to store eight characters. So eight bytes in the file to represent each of the eight flags, whereas by using bit wise operators, we only one bite and we can have each individual bit represent a flag. So back to this calculator less. Now it select binary again. Unless now explain the orbit wise operator. So if I do _PHONE_ _PHONE_ And now I now press for on I press calculate I can see the result is equal toe both of those numbers. Now let's change on a binary digit 20 Doesn't matter which one we now press calculate we still see our original result on the reason for that is because bit wise or it checks the bid against this bit. And if either one of them is one than the resulting bid is one. So if these are both zero and I press calculate, we see that But if this 10 here but this one here is still one, then we still see the same number. If I now change this 1 to 0 press calculate, we now see zero. So once again, the process of checks that this number here is one All this number is one. And if either one if either of those is one than that, resulting bit is also one. So let's now use our bit wise or in our program so firstly giver to this, if statement on put a zero here instead of a one. So this is decimal 254 which can be seen by doing this If we now compel that we can see that this binary number is equivalent to 255 4 decimal. So what if we want to set our special flag in a while? A bit wise or operating is great. For that. We can literally go a equals a special flag. So you use this little line to represent the bit wise or so. If we can pilot now, we can see 255 So what's happened is it's done a bit wise or on a on our special flag. So the process has gone through and it said, Okay, we see a zero here on our special flag. Um, is there one in a Yes, there is. So this resulting bit is one, and it does the same. Here. Is this one? No, it isn't. Is this one? Yes, it is. And this goes on and on until our final bid. Andi were a final bit. Now on we say, Is this one? Yes, it is. Is this one? No, it isn't. But because this is a bit wise or on, this is one than the final result in bit. Must be one on that equals to 255 decimal. So that is how you can do the bit wise. All in C. I should also mention you can also append it like this or equals. So that says, What? Changing variable a onda We're gonna do a bit wise or on our special flag, so that basically the same saying a equals a bit wise or special flag. It's exactly the same, much like you can do, plus equals or minor Sequels when you're dealing with normal numbers and not bit wise operations that we're now going to discuss. Bit wise. Xar. Now what X Or does if the bits is not equal to the other one than the result is one? So, for example, if all of these was zeros 123412348 zeros, we press calculate, we see all ones. If this one is changed to one, we see this one's become zero because both of those are one. If this one become zero, we can see this one become zero because this bit on this bit are zero. So that's what X or is. So I've created to Charles here to represent thes binary numbers on We're gonna perform an ax or on them. So go and sign Shaw. Results equals a be. So just use this little arrow character here to represent that. And that is our ex operator. So I can Now I put the results and we should see decimal one, which we do. We see decimal one. So what happens is our results is equal. 20 b _PHONE_ Garroted finals. He would put a one on the end. So _PHONE_ zeros and a one on the end in binary. That's what is equal to on this finery. Number is equivalent to decimal one. So that is basically the X or inaction. So what's happening is it's going here. Is this one? Yes. Is this one? Yes. Okay, because they're both the same. That zero so and a zero goes there and it does there seven times and it comes to our final bid and it says, Is this the same as the one and be? No, it isn't. So the result must be a one. So that is basically the bit wise. Excell, Let's now discuss bit wise, not so all a bit wise? Not does is it basically flips the beds. So if we did _PHONE_ and we pressed Compute! We get zeros if we did. 123 for 1234 We get 00001111 So, basically the bitten if the bits one become zero if the bed Syria becomes one on this is done on one operate and there isn't too like there is with all the other operators I've just shown. So that is basically bit wise. Not so. I'm now going to show you how it's perform of it wise, not in C. All we do is a scared of this. We go, a unsigned Shaw results equals and in this little swirly character on a that's all it does. So this will flip the bits so the result will be equal to _PHONE_ That's what the result will be equal to. It affect the bits. Eso we should see decimal one out. Put it here. Let's try that. Compile a and we see decimal one. So that's your bit wise. Not Let's now explain bit shifting. So essentially you can shift bits to the left or to the right, and that's pretty cool. So let me show you how to do that. All we do is we say result equals a and we do, too. Left errors zero p. _PHONE_ Put a one at the end there. What that says is shift a one to the left. That's what I says. So if we now compile that, you can see to fight, too, do that 248 So this shifts the bits to the left. That's basically what's happening here. And you can also shift to the right by doing to write house Kampala 63. So that is bit shifting. It basically allows you to shift the bits to the left or to the right. So I expressed. This is binary, but you can use one here is well, so this means shift one bit to the right. This means shift one bit to the left. So let me show you how to do that with the bit wise shift calculator online Just so just so you can instead, a bit more So we have four ones here. Eight ones here we have and we want to shift one to the left. So press shift, we can see the binary is now. 123456789 It's now nine bits in length because we shifted one to the left. But in the process, it doesn't quite work like that. If you if you overflow the register size basically the size, the maximum size. What? You can store the data, then that is discarded. So all we would see is thes that I've selected here. So essentially by by shifting all of that to the left by one, we actually end up with zero as our first bed. Here on that is what happens because we've shifted it and the final bits just carded. If you shift to the right, then you'll notice we have _PHONE_ only seven bits now. So likewise, there would be a zero here that you can't see on this calculator. But that's how would look so if I just get a note pad quickly. It would be that so by shifting to the right by one, we lose our final bit here at the top. On that come zero 39. Argc And Argv: All right, let s discuss Oxy Analogue V. So these two variables combined describe information passed to you When the program starts. Now, Oxi will contain the following of this excusable. That's the first thing that contains. And then anything else after that is options and values passed through our program just before it runs. Now, I know this might seem a bit confusing to you, but just bear with me and follow what I'm doing, and it will all make sense. So what we're first going to do is we're gonna say if Oxy equals one print f no arguments provided Return minus one. And I we're now going to go four inches. I equals zero I below Oxy I plus plus so nice followed print F R V I, and you also need to put the percent s for backslash end by here as well. So the coach should like that. It's pretty straightforward. You're a bit confused now, but as soon as we run this, you'll understand. I promise. Compile that with GCC main dot C Dachau main run made you see no arguments provided. Okay, so then type main. Hello? Now what? You see that you see May now put it and you see Hello. Some main is three excusable that we have running and hello is the second argument. So essentially what happens is main Hello, How are you? You can see after each space is a separate argument. So essentially, what's happening is what we


text:
Course Descriptions for PHYS 1404
PHYS 1404 (4 Credit Hours)
Offered at BHC, CVC, EFC, ECC, MVC, RLC
This is a Texas Common Course Number. This is a Core Curriculum course selected by the colleges of DCCCD.
Prerequisite: DREA 0093 or English as a Second Language (ESOL) 0044 or have met the Texas Success Initiative (TSI) standard in Reading.
Course Description: Introduction to the solar system and the historical development of astronomical ideas. Topics include the study of the celestial sphere, the planets and their satellites, the sun and other objects in the solar system. Emphasis is on the application of scientific principles and explanation of phenomena in the solar system. The laboratory includes outdoor viewing sessions, constellation identification and the use of telescopes (3 Lec., 3 Lab.)
Coordinating Board Academic Approval Number _PHONE_
Designated by the Texas Higher Education Coordinating Board for transfer among community colleges and state public four year colleges and universities as freshman and sophomore general education courses.
Designated by the Texas Higher Education Coordinating Board as workforce education (technical) courses offered for credit and CEUs (Continuing Education Units). While these courses are designed to transfer among state community colleges, they are not designed to automatically transfer to public four-year colleges and universities.

source: m-a-p/FineFineWeb


text:
PHOTO CALL: Arcadia Opens on Broadway; Arrivals, Curtain and Party
18 Mar 2011
Tony Award winner Billy Crudup, who made his Broadway debut in the original New York production of Arcadia, takes on a new role in the Broadway revival of Tom Stoppard's witty and poignant literary work, which officially opened March 17 at the Barrymore Theatre.
Set in both 1809 and the present, Arcadia straddles two centuries to chase a mystery surrounding Lord Byron and the death of a young poet. Crudup played Septimus Hodge in the play's Broadway debut and now takes on the role of literary academic Bernard Nightingale.
The Broadway production is based on the 2009 London revival, which five-time Tony Award-nominated director David Leveaux staged at the Duke of York's Theatre. Leveaux repeats his work for the Broadway revival, which began previews Feb. 26. The production is billed as a limited engagement through June 19.
Arcadia, according to producers, "is set in April 1809 in a stately home in Derbyshire. Thomasina, a gifted pupil, proposes a startling theory, beyond her comprehension. All around her, the adults, including her tutor Septimus, are preoccupied with secret desires, illicit passions and professional rivalries. Two hundred years later, academic adversaries Hannah and Bernard (Williams and Crudup) are piecing together puzzling clues, curiously recalling those events of 1809, in their quest for an increasingly elusive truth."
For tickets visit Telecharge. The Barrymore Theatre is located at 243 West 47th Street.
Holed up in a seedy motel on the edge of the Mojave Desert, two former lovers unpack the deep secrets and dark desires of their tangled relationship, passionately tearing each other apart. Led by director Daniel Aukin (Back Back Back at MTC, 4,000 Miles), Tony winner Nina Arianda (Venus in Fur at MTC, Born Yesterday) and Sam Rockwell (A Behanding in Spokane, The Way Way Back) bring an explosive intensity to Sam Shepard's (Buried Child, True West) landmark myth of the new Wild West.


text:
A ten-year study shows that Asian black bears' diets vary greatly depending on sex, stage of life, and resource availability, providing important information on foraging strategy according to age-sex classes. Researchers at Tokyo University of Agriculture and Technology (TUAT) in Japan published their findings on April 15 in Mammal Study.
- Over 80% of Atlantic Rainforest remnants have been impacted by human activity
- 'Miracle poison' for novel therapeutics
- Paleontologists discover new insect group after solving 150-year-old mystery
- Tool that more efficiently analyzes ocean color data will become part of NASA program
- Bearded seals are loud – but not loud enough

source: openbmb/Ultra-FineWeb


text:
Binzhou, China (PRWEB) July 04, 2014
Huahai Vitiligo Hospital published twelve texts in 2014 to detail major breakthroughs in the treatment of vitiligo. These breakthroughs are the result of combining the practices of both traditional Chinese medicine and modern medicine. Huahai Vitiligo Hospital believes that receiving proper vitiligo treatment is now a world-wide issue, due to the steady increase in reported cases. Because traditional approaches alone historically have not delivered a successful treatment method, Huahai has combined elements of modern medicine with traditional Chinese medicines to provide a holistic, successful cure for vitiligo.
Due to the imminent demand for innovative vitiligo treatment, the Huahai Vitiligo Hospital has published twelve medical texts this year to detail their holistic approach. These publications include, The Research of Vitiligo, New Theory of Vitiligo, The Vitiligo Therapeutics, The Treatment and Nursing of Vitiligo and Vitiligo Nutrition. These books are the result of 20 plus years of research completed by Dr. Cheng Aihua and her scientific research team.
Dr. Cheng Aihua, a renowned scientific researcher and the director of Huahai Vitiligo Hospital explains, "These works cover everything from vitiligo pathogenesis research to theories of new technological developments, from effective clinical and psychological nursing methods to supplemental diet research. These works provide complete, thorough and systematic vitiligo treatment options. We have mastered vitiligo occurrence, development patterns, and a holistic treatment philosophy, which marks the end of vitiligo being considered an incurable condition."
Dr. Cheng Aihua is celebrated for her expertise in traditional Chinese medicine. She has been engaged in vitiligo research for 30 years, which qualifies her rich experience in the theory and diagnosis of vitiligo. She famously formulated the theory "Black and White Cured Together", which is now an industry standard for treating vitiligo. This technique marked a major breakthrough in eliminating or isolating the cause of vitiligo, controlling its development and activating pigment regeneration. Her research signifies the end of vitiligo being deemed incurable, and thus begins new era for modern medicine. This technology has already benefited over a hundred thousand patients worldwide. Dr. Cheng Aihua is considered the highest level authority in the scientific research of vitiligo treatment.
These twelve new research based works integrate both practicability and science; they represent the forefront of vitiligo research. These texts detail new results, technology and methods, and incorporate both traditional Chinese medicine and modern medicine to accurately treat vitiligo.
About Huahai Vitiligo Hospital
Huahai Vitiligo Hospital is based in Binzhou, China and is supported by the United Nations as a scientific demonstration base for the diagnosis and treatment of vitiligo. This organization implements the newest technology of "BWCT", which has successfully cured thousands vitiligo patients. Huahai's information is translated into more than 100 languages. Their mission is to provide services to vitiligo patients worldwide.


Mongameli Mabona
His Life and Work
Ernst Wolff
Regular price €0.00 Sale
Edited volume - free ebook - ePUB
VIEW Edited volume - free ebook - PDF VIEW Monograph - paperback
The life and work of a remarkably versatile and pioneering South African thinker
Mongameli Anthony Mabona (1929) is a singular South African scholar with an exceptional life path. Yet, he is a wrongly forgotten figure today. British imperialism and apartheid shaped the world into which he was born and, to a large extent, these powers carved out his destiny for him. Nevertheless, a curious set of coincidences enabled him to obtain a tertiary education as a priest, to pursue his doctoral studies in Italy and to befriend Alioune Diop. He is one of the first published philosophers of Anglophone Africa and holds doctorates in theology and anthropology. His opposition to institutionalized racism – an opposition which included his co-authoring the 1970 "Black Priests' Manifesto" – eventually led to his exile. This book is the first study of any kind devoted to Mabona. It documents his life and offers a synoptic reading of his scholarly and poetic work.
Ebook available in Open Access.
1. Xhosaland: A history of confrontations
1. A snapshot of Xhosa life in the mid eighteenth century
2. Accelerated change: A typology of mounting conflict
3. A changing region in a changing world
3.1 Spread of Boers and British expansion
3.2 British domination and its effects on Xhosaland and beyond
3.3 Changes from the Xhosaland perspective
3.4 Changes from the broader South African perspective
2. (Dis)Union: The world of Mabona's youth (1910 to the mid 1950s)
1. International and Union politics
2. The economy
3. Separation – reserves – labour
4. Transkei: Culture, religion, education
5. Resistance nationally and in the Transkei
3. Enter Mongameli
1. Birth and first years
2. Early childhood in Qombolo
3. Life in Zigudu – Catholic background (1)
4. Ixopo – Catholic background (2)
5. Pevensey – Catholic background (3)
6. Early priesthood
4. Italy
1. Italian society after World War II
2. Everyday life in Rome
3. Mabona, the student and researcher
4. Further intellectual work
5. Second Congress of Black Writers and Artists: Alioune Diop and Présence Africaine
Excursion: The journal Présence Africaine
6. Preparing for Vatican II
5. Back home? Apartheid, St. Peter's, SPOBA
1. Apartheid
2. Apartheid education
3. The South African economy in the 1960s
4. Resistance
4.1 The ANC and the PAC
5. Life back in South Africa
5.1 Lumko
5.2 Independent ethnographic studies
5.3 Poetry
5.4 Lecturer at St. Peter's in Hammanskraal
6. London and Switzerland: Politics or anthropology?
1. SOAS
2. The Azanian People's Liberation Front and other politics
3. Family life
4. Continued research
1. Lux: The first impetus
2. Présence Africaine: Writing for a wide public
3. "The depths of African philosophy" and The outlines of African philosophy
3.1 General appraisal: South Africa's first African philosopher? 1
4. Dissertatio ad lauream in Facultate Juris Canonici apud Pontificiam
Universitatem Urbanianam
5. "The nuclear blast of spring": Poetry
6. Writings of a South African priest
7. Anthropology and religion
8. Interlude: The publication spurt of 1996
9. Diviners and prophets: The last, incomplete, work
9.1 Final appraisal
Mabona primary bibliography
Notes on the sources for interviews and biography
Format: Edited volume - free ebook - ePUB
202 pages
ISBN: 9789461663627
Publication: January 05, 2021
Languages: English
Ernst Wolff is professor of philosophy at the Institute of Philosophy, KU Leuven.


text:
Trumpf has developed BrightLine Speed, a new technology for cutting sheet metal faster and more efficiently. The solution is aimed in particular at the three-dimensional cutting of hot-formed components, such as those used in the manufacture of B-pillars or door frames in automotive production.
"With BrightLine Speed, we can increase cutting speed by up to 60 percent for sheets up to four millimeters thick," says Ralf Kohllöffel, product manager at Trumpf. Another advantage is that BrightLine Speed reduces cutting gas consumption per component by around half compared to conventional laser cutting. In addition, the cutting process can be 15 percent more productive with the same laser power, which is why correspondingly less energy is required per component. "Our new cutting technology results in noticeable leaps in productivity and cost savings for our customers through more speed and less gas consumption," says Kohllöffel.
Two fibers in one cable
The central component of BrightLine Speed is a Trumpf-patented 2in1 laser light cable (LLK) with an inner and an outer fiber core. A TruDisk disk laser couples laser light into the LLK and distributes the laser power to the inner and outer cores using a so-called wedge switch. This allows the laser's power and beam profile to be flexibly adapted to the sheet thickness to be processed better than would otherwise be possible.


NewsNational News
Many seniors don't have internet access, a crucial resource amid the pandemic
Posted at 2:27 PM, Feb 08, 2021
and last updated 2021-02-08 15:27:29-05
Two in five seniors do not have internet access. That translates to 20 million older adults in the United States, according to Older Adults Technology Services, also known as OATS.
Internet access has always been important, but it has become even more essential during the pandemic. Seniors are missing out on a lot of essential needs if they don't have the internet.
That can include things like online banking, ordering groceries, and socializing with friends and family. They may also be missing out on crucial information about the coronavirus vaccine.
"A lot of people are wanting to sign up for the vaccines and there's an absolute mess with a lot of older people who are trying to get in and register. And virtually all those registrations are online," said Tom Kamber, Executive Director of OATS.
Registering for vaccines online is the quickest way to get in line, which may be a big incentive for a senior to get internet access. They may also want it for other reasons.
If you want to help out, first ask them what they want to do with internet. That can help you find the appropriate tools for them to get online.
Experts at OATS say it's important they have a large screen that's at least eleven inches. Using a smartphone won't be very helpful.
"We strongly recommend that people get a decent stable wireline connection at home if they can. They don't need spectacular speeds. They don't need 100 gigabytes or something like that. A basic consumer online connection is really critical," said Kamber.
There are resources to help older adults with computer and internet skills. offers free classes on the basics to specific things like banking and video chatting.


text:
Across East Africa, only 1 in 6 pupils in Standard 3 passed a Standard 2 English test
Across East Africa, children from poorer households perform worse on tests at all ages
Our District level results show there is substantial geographic variation in literacy and numeracy skills within each country.
There are minimal differences between boys and girls in their literacy and numeracy skills, although girls outperform boys in the lower grades
Two in every 10 children in Standard 7 in East Africa do not have Standard 2 level literacy and numeracy competencies
The gap in results between public and private schools is largest in Tanzania
Uwezo means 'capability' in Kiswahili. Uwezo is a four year initiative that aims to improve competencies in literacy and numeracy among children aged 6-16 years old in Kenya, Tanzania and Uganda, by using an innovative approach to social change that is citizen driven and accountable to the public.

source: HuggingFaceFW/fineweb-edu


text:
June 17, 2010 in Learning Jazz
Brent Jensen, Origin Saxophone Recording Artist and Professor of Jazz Studies at the College of Southern Idaho, tells us how he approaches learning tunes. This is his third video in the series (Part 1 has two parts). The original handout is also below as well as text and a.pdf document. Enjoy! Make sure to check out all of Brent's videos!
Brent Jensen's Recordings
Feel free to listen to some of this awesome material Brent recorded. He's got some great stuff! It's just fun to hear a sample of what he has recorded. Also, any purchases of these songs or albums made through this site will help Brent Jensen, Origin records, and this website will even get a little kickback from anything you order through Amazon. We appreciate your support so we can continue the website! Thank you.
SEVEN STEPS TO HEAVEN
by Brent Jensen
(with thanks to Jiggs Whigham)
1. Memorize the melody. Listen to a wide variety of recordings of the song. Work on playing the song in different keys, tempos and styles. Try to exhaust the melodic possibilities of the song and absorb it into your subconscious.
2. Memorize the form of the song (blues, AABA, etc.) and the chord progression. Play through the entire form using root/third/fifth patterns on the changes. Play through the form using whole notes & half notes (background figures) and quarter notes (as in a bass line).
3. Play through the tune using short, repeated rhythmic patterns (riffs) and note groupings (non-repetitive) of three to seven notes.
4. Play using long, connected lines (mostly eighth notes) without breaking the flow. Concentrate on creating as much density (ala Coltrane) as possible.
5. Play using very few notes and relying primarily on color (vibrato, bends, growls, sub-tone, etc.) and space. Concentrate on creating as much space (ala Miles) as possible.
6. Work on varying articulation by playing through the tune entirely in a legato style and then again in a marcato style. Experience the extremes of each method of attack and work to integrate them more naturally into your playing style.
7. Work on the elasticity of your time conception by playing "on top" of the beat, "behind" the beat (laying back) and "ahead" of the beat (rushing). Practice with a metronome set for "2 and 4" (ie: the drummer's hi-hat) and on all four beats (ie: a walking bass line).
For more posts by Brent Jensen, you can go to:
No related posts.
Related posts brought to you by Yet Another Related Posts Plugin.


text:
In this study, a hydrodynamic model was used that includes the effects of wave–current interactions to simulate the wave and current patterns before and after offshore wind turbine installation in western Taiwan. By simulating the waves and currents after the offshore wind turbine was established, the waves and currents caused by the wind turbine were seen to have a limited range of influence, which is probably within an area about four to five times the size of the diameter (12–15 m) of the foundation structure. Overall, the analysis of the simulation results of the wave and current patterns after the offshore wind turbines were established shows that the underwater foundation only affected the local area near the pile structure. The wind farm (code E) of the research case can be equipped with about 720 cage cultures; if this is extended to other wind farms in the western sea area, it should be possible to produce economic-scale farming operations such as offshore wind power and fisheries. However, this study did not consider the future operation of the entire offshore wind farm. If the operation and maintenance of offshore wind farms are not affected, and if the consent of the developer is obtained, it should be possible to use this method to provide economically large-scale farming areas as a mutually beneficial method for offshore wind power generation and fisheries.
This is an open access article distributed under the Creative Commons Attribution License
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited


text:
Faculty Resources for the CompTIA A+ Exam (220-901/220-902)
The A+ certification is an entry-level industry credential for people who want or need to demonstrate their competency as computer repair technicians. The A+ credential requires that you pass two separate computer-based tests:
220-901, also known as "The hardware exam"
220-902, also known as "The software exam"
With your knowledge of best practices, continual guidance and encouragement to the student's goal, ECPI University students can conquer the A+ Certification goal and be better equipped for entering a new career.


Books tagged: the scarlet letter
Found 2 results
Aprenda Ingles! Learn Spanish! LA LETRA ESCARLATA: En Ingles y Espanol
Price: $2.99 USD. Words: 139,320. Language: English. Published: April 21, 2012 by Kryptic Books. Category: Fiction » Historical » USA
THE SCARLET LETTER/LA LETRA ESCARLATA: This unique book features paragraph by paragraph translations from English to Spanish, allowing the reader to learn Spanish vocabulary and sentence structure while enjoying a classic. This is a fun and affordable way to learn a second language. Previous experience with Spanish is recommended, but ambitious beginners are welcome to give it a try.
The Scarlet Letter: Review Guide
Price: $2.99 USD. Words: 5,110. Language: English. Published: February 17, 2013. Category: Nonfiction » Education and Study Guides » Study guides - Literature
This eBook is a short and concise review guide of The Scarlet Letter by Nathaniel Hawthorne. The review includes a short summary of the whole novel, major themes in the novel and explanations of those themes relations to the book, a character guide with brief details on the characters, and chapter reviews written in bullet point that go into more detail than the book summary.


Главная / Zend Manual Core
Using Google Spreadsheets
Using Google Apps Provisioning
Google Apps is a service which allows domain administrators to offer their users managed access to Google services such as Mail, Calendar, and Docs & Spreadsheets. The Provisioning API offers a programmatic interface to configure this service. Specifically, this API allows administrators the ability to create, retrieve, update, and delete user accounts, nicknames, groups, and email lists.
This library implements version 2.0 of the Provisioning API. Access to your account via the Provisioning API must be manually enabled for each domain using the Google Apps control panel. Only certain account types are able to enable this feature.
For more information on the Google Apps Provisioning API, including instructions for enabling API access, refer to the » Provisioning API V2.0 Reference.
Note: Authentication
The Provisioning API does not support authentication via AuthSub and anonymous access is not permitted. All HTTP connections must be authenticated using ClientAuth authentication.
Setting the current domain
In order to use the Provisioning API, the domain being administered needs to be specified in all request URIs. In order to ease development, this information is stored within both the Gapps service and query classes to use when constructing requests.
Setting the domain for the service class
To set the domain for requests made by the service class, either call setDomain() or specify the domain when instantiating the service class. For example:
 1. $domain = "example.com";
 2. $gdata = new Zend_Gdata_Gapps($client, $domain);
Setting the domain for query classes
Setting the domain for requests made by query classes is similar to setting it for the service class-either call setDomain() or specify the domain when creating the query. For example:
 1. $domain = "example.com";
 2. $query = new Zend_Gdata_Gapps_UserQuery($domain, $arg);
When using a service class factory method to create a query, the service class will automatically set the query's domain to match its own domain. As a result, it is not necessary to specify the domain as part of the constructor arguments.
 1. $domain = "example.com";
 2. $gdata = new Zend_Gdata_Gapps($client, $domain);
 3. $query = $gdata->newUserQuery($arg);
Interacting with users
Each user account on a Google Apps hosted domain is represented as an instance of Zend_Gdata_Gapps_UserEntry. This class provides access to all account properties including name, username, password, access rights, and current quota.
Creating a user account
User accounts can be created by calling the createUser() convenience method:
 1. $gdata->createUser('foo', 'Random', 'User', '••••••••');
Users can also be created by instantiating UserEntry, providing a username, given name, family name, and password, then calling insertUser() on a service object to upload the entry to the server.
 1. $user = $gdata->newUserEntry();
 2. $user->login = $gdata->newLogin();
 3. $user->login->username = 'foo';
 4. $user->login->password = '••••••••';
 5. $user->name = $gdata->newName();
 6. $user->name->givenName = 'Random';
 7. $user->name->familyName = 'User';
 8. $user = $gdata->insertUser($user);
The user's password should normally be provided as cleartext. Optionally, the password can be provided as an SHA-1 digest if login->passwordHashFunction is set to 'SHA-1'.
Retrieving a user account
Individual user accounts can be retrieved by calling the retrieveUser() convenience method. If the user is not found, NULL will be returned.
 1. $user = $gdata->retrieveUser('foo');
 2.
 3. echo 'Username: ' . $user->login->userName . "\n";
 4. echo 'Given Name: ' . $user->name->givenName . "\n";
 5. echo 'Family Name: ' . $user->name->familyName . "\n";
 6. echo 'Suspended: ' . ($user->login->suspended ? 'Yes' : 'No') . "\n";
 7. echo 'Admin: ' . ($user->login->admin ? 'Yes' : 'No') . "\n"
 8. echo 'Must Change Password: ' .
 9. ($user->login->changePasswordAtNextLogin ? 'Yes' : 'No') . "\n";
 10. echo 'Has Agreed To Terms: ' .
 11. ($user->login->agreedToTerms ? 'Yes' : 'No') . "\n";
Users can also be retrieved by creating an instance of Zend_Gdata_Gapps_UserQuery, setting its username property to equal the username of the user that is to be retrieved, and calling getUserEntry() on a service object with that query.
 1. $query = $gdata->newUserQuery('foo');
 2. $user = $gdata->getUserEntry($query);
 3.
 4. echo 'Username: ' . $user->login->userName . "\n";
 5. echo 'Given Name: ' . $user->login->givenName . "\n";
 6. echo 'Family Name: ' . $user->login->familyName . "\n";
 7. echo 'Suspended: ' . ($user->login->suspended ? 'Yes' : 'No') . "\n";
 8. echo 'Admin: ' . ($user->login->admin ? 'Yes' : 'No') . "\n"
 9. echo 'Must Change Password: ' .
 10. ($user->login->changePasswordAtNextLogin ? 'Yes' : 'No') . "\n";
 11. echo 'Has Agreed To Terms: ' .
 12. ($user->login->agreedToTerms ? 'Yes' : 'No') . "\n";
If the specified user cannot be located a ServiceException will be thrown with an error code of Zend_Gdata_Gapps_Error::ENTITY_DOES_NOT_EXIST. ServiceExceptions will be covered in the exceptions chapter.
Retrieving all users in a domain
To retrieve all users in a domain, call the retrieveAllUsers() convenience method.
 1. $feed = $gdata->retrieveAllUsers();
 2.
 3. foreach ($feed as $user) {
 4. echo " * " . $user->login->username . ' (' . $user->name->givenName .
 5. ' ' . $user->name->familyName . ")\n";
 6. }
This will create a Zend_Gdata_Gapps_UserFeed object which holds each user on the domain.
Alternatively, call getUserFeed() with no options. Keep in mind that on larger domains this feed may be paged by the server. For more information on paging, see the paging chapter.
 1. $feed = $gdata->getUserFeed();
 2.
 3. foreach ($feed as $user) {
 4. echo " * " . $user->login->username . ' (' . $user->name->givenName .
 5. ' ' . $user->name->familyName . ")\n";
 6. }
Updating a user account
The easiest way to update a user account is to retrieve the user as described in the previous sections, make any desired changes, then call save() on that user. Any changes made will be propagated to the server.
 1. $user = $gdata->retrieveUser('foo');
 2. $user->name->givenName = 'Foo';
 3. $user->name->familyName = 'Bar';
 4. $user = $user->save();
Resetting a user's password
A user's password can be reset to a new value by updating the login->password property.
 1. $user = $gdata->retrieveUser('foo');
 2. $user->login->password = '••••••••';
 3.


Date of Award
Document Type
Degree Name
Doctor of Philosophy (PhD)
First Advisor
Cornelia Yarbrough
The purpose of this study was to examine performance trends of advanced wind instrumentalists with regard to intervallic tuning. Factors of interest were tuning system, location (above or below a referential stimulus), interval type, and group (student or professional). Also of interest was the direction of deviation of the target pitches, sharp or flat, from equal temperament. Subjects (N = 16) were experienced wind instrumentalists, eight experienced professionals, and eight advanced university students. Subjects were recorded performing a two-part reduction of a Bach chorale, first playing the melody with a synthesized harmony line, then vice versa. Performances were transferred to a NeXT computer where target intervals were analyzed and converted to cent distance. Results indicated that overall cent deviation was greatest when compared to just tuning and least when compared to equal tempered tuning. For cent deviation from equal temperament, thirds and sixths were performed slightly less in-tune than fourths, fifths, unisons, and octaves. Location also affected the direction of deviation from equal temperament as it appeared that subjects tended to play sharp and less in-tune when performing below the stimulus. There were no differences found between groups for the magnitude of deviation, however, considering direction of deviation from equal temperament, it was observed that the student group performed less sharp than the professionals when performing below the stimulus and less in-tune when performing above.


text:
The following Participating Institutions are custodians for this species in the CPC National Collection:
Missouri Botanical Garden
The conservation of Lesquerella stonensis is fully sponsored.
Kimberlie McCue, Ph.D. contributed to this Plant Profile.
The Stones River bladderpod is a showy member of the mustard family, producing fragrant white flowers. This rare annual requires habitat disturbance in order to complete its life-cycle. Historically, the floodplain habitat it was found in was maintained by regular flooding, which removed competitive perennial grasses and woody plants. With alterations to the waterways where this species occurs, flooding no longer maintains the habitat this plant needs. Now, ironically, further alteration to the environment is keeping this plant alive, as annual crop production is the primary way to artificially maintain the habitat this species needs--as long as there is no fall planting or herbicide use.
In some years the plant is quite abundant locally, but virtually absent in others. A persistent seed bank seems to be important in the persistence of this plant within its narrow range in the floodplains of the Stones River.
Distribution & Occurrence
Open areas of the Stones River floodplain--primarily in disturbed areas such as pastures, agricultural fields and roadsides. (USFWS 1999)
|The number of sites with plants evident above ground varies from year to year. There are only a few sites that seem to be well established, however, in some years up to 20 sites can be found with plants extant. (USFWS 1999)|
Conservation, Ecology & Research
Loss of habitat through land conversion (via residential, commercial, or industrial development)
A three year monitoring program was completed in 1997. Sites studied were on the U.S. Army Corps of Engineers property on J. Percy Priest Reservoir.
Carol J. Baskauf, a researcher at Austin Peay State University, is studying the population genetics of this species (Baskauf 2001)
Shaw, E.A. 1973. The Genus Lesquerella (Cruciferae) in North America. Cambridge, Mass.: Harvard University Press.
USFWS. 1994. Determination of Endangered or Threatened Status for 21 Plants from the Island of Hawaii, State of Hawaii. Federal Register. 59, 43: 10305-10325.


text:
Artificial ground surfaces (pitches) containing recycled rubber tyre crumb have been used for a range of sports and other recreational uses for several decades. However, concern has been raised over the potential link between the use of these artificial pitches and a range of adverse health outcomes, particularly cancers. Much of the concern relates to chemical substances potentially contained within the rubber granulate infill.
A number of reviews have been conducted of the potential health impacts of tyre crumb in sports pitches (Norwegian Institute of Public Health and the Radium Hospital 2006, New York State Department of Health 2009, Washington State Department of Health 2017). Two of the most significant and recent reviews of the chemical risks posed by rubber infill to human health have been published by the European Chemicals Agency (ECHA, 2017) and the National Institute for Public Health in the Netherlands (RIVM, 2017).
Health Protection Scotland (HPS) has considered the findings of these reviews in order to assess the evidence on the potential health impacts of rubber tyre crumb used in artificial ground surfaces.


Sign up ×
Let $x(n)$ be the solution to the following equation $$ x=-\frac{\log(x)}{n} \quad \quad \quad \quad (1) $$ as a function of $n,$ where $n \in \mathbb N.$ How would you find the asymptotic behaviour of the solution, i.e. a function $f$ of $n$ such that there exist constants $A,B$ and $n_0\in\mathbb N$ so that it holds $$Af(n) \leq x(n) \leq Bf(n)$$ for all $n > n_0$?
share|cite|improve this question
1 Answer 1
Call $u_n:t\mapsto t\mathrm e^{nt}$, then $x(n)$ solves $u_n(x(n))=1$. For every $a$, introduce $$ x_a(n)=\frac{\log n}n-a\frac{\log\log n}n. $$ Simple computations show that, for every fixed $a$, $u_n(x_a(n))\cdot(\log n)^{a-1}\to1$ when $n\to\infty$. Thus, for every $a\gt1$, there exists some finite index $n(a)$ such that $x(n)\geqslant x_a(n)$ for every $n\geqslant n(a)$, and, for every $a\lt1$, there exists some finite index $n'(a)$ such that $x(n)\leqslant x_a(n)$ for every $n\geqslant n'(a)$. Finally, when $n\to\infty$, $$ nx(n)=\log n-\log\log n+o(\log\log n). $$ The assertion in your post holds with $f(n)=(\log n)/n$, $n_0=\max\{n(A),n'(B)\}$, $B=1$ and every $A\lt1$.
share|cite|improve this answer
The solution can be written as $x_n=W(n)/n$, where $W$ is Lambert's function. – Julián Aguirre Mar 8 '12 at 9:21
Your Answer


text:
The axis of Earth makes a 23.5° angle with a direction perpendicular to the plane of Earth's orbit. As shown in Figure 10.41, this axis precesses, making one complete rotation in 25,780 y. (a) Calculate the change in angular momentum in half this time. (b) What is the average torque producing this change in angular momentum? (c) If this torque were created by a single force (it is not) acting at the most effective point on the equator, what would its magnitude be?
Step-by-step solution Step 1 of 9 The change in angular momentum in half its time is calculated as, Here is the angular momentum of the earth about its axis, is the moment of inertia of the Earth and is the angular velocity of the axis.


Release: 1.4.15 current release | Release Date: May 11, 2021
SQLAlchemy 1.4 Documentation
Mapping Table Columns
The default behavior of mapper() is to assemble all the columns in the mapped Table into mapped object attributes, each of which are named according to the name of the column itself (specifically, the key attribute of Column). This behavior can be modified in several ways.
Naming Columns Distinctly from Attribute Names
A mapping by default shares the same name for a Column as that of the mapped attribute - specifically it matches the Column.key attribute on Column, which by default is the same as the
The name assigned to the Python attribute which maps to Column can be different from either or Column.key just by assigning it that way, as we illustrate here in a Declarative mapping:
class User(Base):
 __tablename__ = 'user'
 id = Column('user_id', Integer, primary_key=True)
 name = Column('user_name', String(50))
Where above resolves to a column named user_id and resolves to a column named user_name.
When mapping to an existing table, the Column object can be referenced directly:
class User(Base):
 __table__ = user_table
 id = user_table.c.user_id
 name = user_table.c.user_name
The corresponding technique for an imperative mapping is to place the desired key in the dictionary with the desired key:
mapper_registry.map_imperatively(User, user_table, properties={
 'id': user_table.c.user_id,
 'name': user_table.c.user_name,
In the next section we'll examine the usage of.key more closely.
Automating Column Naming Schemes from Reflected Tables
In the previous section Naming Columns Distinctly from Attribute Names, we showed how a Column explicitly mapped to a class can have a different attribute name than the column. But what if we aren't listing out Column objects explicitly, and instead are automating the production of Table objects using reflection (e.g. as described in Reflecting Database Objects)? In this case we can make use of the DDLEvents.column_reflect() event to intercept the production of Column objects and provide them with the Column.key of our choice. The event is most easily associated with the MetaData object that's in use, such as below we use the one linked to the declarative_base instance:
_USER_.listens_for(Base.metadata, "column_reflect")
def column_reflect(inspector, table, column_info):
 # set column.key = "attr_"
 column_info['key'] = "attr_%s" % column_info['name'].lower()
With the above event, the reflection of Column objects will be intercepted with our event that adds a new ".key" element, such as in a mapping as below:
class MyClass(Base):
 __table__ = Table("some_table", Base.metadata,
The approach also works with the Automap extension. See the section Intercepting Column Definitions for background.
Naming All Columns with a Prefix
A quick approach to prefix column names, typically when mapping to an existing Table object, is to use column_prefix:
class User(Base):
 __table__ = user_table
 __mapper_args__ = {'column_prefix':'_'}
The above will place attribute names such as _user_id, _user_name, _password etc. on the mapped User class.
This approach is uncommon in modern usage. For dealing with reflected tables, a more flexible approach is to use that described in Automating Column Naming Schemes from Reflected Tables.
Using column_property for column level options
Options can be specified when mapping a Column using the column_property() function. This function explicitly creates the ColumnProperty used by the mapper() to keep track of the Column; normally, the mapper() creates this automatically. Using column_property(), we can pass additional arguments about how we'd like the Column to be mapped. Below, we pass an option active_history, which specifies that a change to this column's value should result in the former value being loaded first:
from sqlalchemy.orm import column_property
class User(Base):
 __tablename__ = 'user'
 id = Column(Integer, primary_key=True)
 name = column_property(Column(String(50)), active_history=True)
column_property() is also used to map a single attribute to multiple columns. This use case arises when mapping to a join() which has attributes which are equated to each other:
class User(Base):
 __table__ = user.join(address)
 # assign "", "address.user_id" to the
 # "id" attribute
 id = column_property(, address_table.c.user_id)
For more examples featuring this usage, see Mapping a Class against Multiple Tables.
Another place where column_property() is needed is to specify SQL expressions as mapped attributes, such as below where we create an attribute fullname that is the string concatenation of the firstname and lastname columns:
class User(Base):
 __tablename__ = 'user'
 id = Column(Integer, primary_key=True)
 firstname = Column(String(50))
 lastname = Column(String(50))
 fullname = column_property(firstname + " " + lastname)
See examples of this usage at SQL Expressions as Mapped Attributes.
Object Name Description
column_property(*columns, **kwargs)
Provide a column-level property for use with a mapping.
function sqlalchemy.orm.column_property(*columns, **kwargs)
Provide a column-level property for use with a mapping.
Column-based properties can normally be applied to the mapper's properties dictionary using the Column element directly. Use this function when the given column is not directly present within the mapper's selectable; examples include SQL expressions, functions, and scalar SELECT queries.
The column_property() function returns an instance of ColumnProperty.
Columns that aren't present in the mapper's selectable won't be persisted by the mapper and are effectively "read-only" attributes.
 - *cols – list of Column objects to be mapped.
 - active_history=False – When True, indicates that the "previous" value for a scalar attribute should be loaded when replaced, if not already loaded. Normally, history tracking logic for simple non-primary-key scalar values only needs to be aware of the "new" value in order to perform a flush. This flag is available for applications that make use of get_history() or Session.is_modified() which also need to know the "previous" value of the attribute.
 - comparator_factory – a class which extends Comparator which provides custom SQL clause generation for comparison operations.
 - group – a group name for this property when marked as deferred.
 - deferred – when True, the column property is "deferred", meaning that it does not load immediately, and is instead loaded when the attribute is first accessed on an instance. See also deferred().
 - doc – optional string that will be applied as the doc on the class-bound descriptor.
 - expire_on_flush=True – Disable expiry on flush. A column_property() which refers to a SQL expression (and not a single table-bound column) is considered to be a "read only" property; populating it has no effect on the state of data, and it can only return database state. For this reason a column_property()'s value is expired whenever the parent object is involved in a flush, that is, has any kind of "dirty" state within a flush. Setting this parameter to False will have the effect of leaving any existing value present after the flush proceeds. Note however that the Session with default expiration settings still expires all attributes after a Session.commit() call, however.
 - info – Optional data dictionary which will be populated into the attribute of this object.
 - raiseload
 if True, indicates the column should raise an error when undeferred, rather than loading the value. This can be altered at query time by using the deferred() option with raiseload=False.
 New in version 1.4.
See also
Using column_property for column level options - to map columns while including mapping options
Using column_property - to map SQL expressions
Mapping a Subset of Table Columns
Sometimes, a Table object was made available using the reflection process described at Reflecting Database Objects to load the table's structure from the database. For such a table that has lots of columns that don't need to be referenced in the application, the include_properties or exclude_properties arguments can specify that only a subset of columns should be mapped. For example:
class User(Base):
 __table__ = user_table
 __mapper_args__ = {
 'include_properties' :['user_id', 'user_name']
…will map the User class to the user_table table, only including the user_id and user_name columns - the rest are not referenced. Similarly:
class Address(Base):
 __table__ = address_table
 __mapper_args__ = {
 'exclude_properties' : ['street', 'city','state', 'zip']
…will map the Address class to the address_table table, including all columns present except street, city, state, and zip.
When this mapping is used, the columns that are not included will not be referenced in any SELECT statements emitted by Query, nor will there be any mapped attribute on the mapped class which represents the column; assigning an attribute of that name will have no effect beyond that of a normal Python attribute assignment.
In some cases, multiple columns may have the same name, such as when mapping to a join of two or more tables that share some column name. include_properties and exclude_properties can also accommodate Column objects to more accurately describe which columns should be included or excluded:
class UserAddress(Base):
 __table__ = user_table.join(addresses_table)
 __mapper_args__ = {
 'exclude_properties' :[],
 'primary_key' : []
insert and


Internet Problem Solving Contest
IPSC 2017
Solution to Problem F – Flipping and cutting
This problem is based on a nice puzzle called "The Ice Cream Cake puzzle". Its origin is unknown, but you can find it, for example, in Peter Winkler's book "Mathematical Mind Benders".
The main interesting thing about this problem is that – contrary to what many people intuitively expect – the answer is always finite, even if the step happens to be irrational. Yes, even if we never cut the circle twice in the same place, it will still always return to the all-black state after finitely many steps. We will now show why that is the case and also how to compute the minimal number of steps needed.
How is that even possible?
The key observation is that the locations of cuts don't necessarily matter. After the cut, we always flip and reverse a part of the circle. If the reversal brings back a piece of the same color, the cut will, for all practical purposes, disappear – as if we never made it.
The only thing that matters are the coordinates at which a white piece touches a black piece. Below, we will call these coordinates borders.
Changing the game
Let's change the game slightly. The new game will be completely equivalent to the old one, but it will be a bit easier to argue about it.
First of all, let's scale everything. From now on, we'll assume that the step length x is an arbitrary real from the open interval (0, 1), and that the circumference of the circle is exactly 1.1
The second change: instead of going around the circle, we will rotate the entire circle by x (measured along its circumference) after each flip. This way we'll get an equivalent process, but we will always be making the cut at the same place, and we will always be flipping a wedge that lies on the same part of the table.
Imagine a fixed coordinate system around the circle. (I.e., the coordinates don't rotate when the circle does, they are written on the table.) The coordinates wrap around the circle – i.e., all operations with them are done modulo 1. For example, the coordinates 0.47, 23.47 and −0.53 all represent the same point.
But back to our game. We will make the first cut at 0. Then, each round will consist of three steps:
A simple special case
The game is simple if the circumference is a positive multiple of x. If it happens to be the case that kx = 1 for a positive integer k, the game clearly ends after 2k steps: first we flip everything upside down in k steps and then we flip it back in another k steps.
The remaining general case
Below, we will deal with the remaining case. Let k = ⌈1/x.
If we start with an all-black circle, the first k − 1 cuts will flip a black wedge to its white side. Then, the k-th cut will cut into the first wedge.
Let's write x = y + z, where y = 1/k. After the first round we have two borders: at 0 and at x. After the second round the borders are at 0 and 2x. After k − 1 rounds the borders are at 0 and (k − 1)x. In the following round we get a new border at x − kz. In the following rounds new borders appear at 2x − kz, 3x − kz, …, (k − 1)x − kz. And that's it. We can easily show that if the current borders are only at some of these coordinates before a round, there will only be borders at some of these coordinates (and nowhere else) after the round.
Finiteness of the game
The current state can be described by specifying the current set of borders and the color of one of the pieces between them. As there are only finitely many possible locations of borders, a state must eventually repeat. As the process is deterministic, it must be eventually periodic. And as the process is reversible, it must be purely periodic. Hence, the first state to repeat must be the initial state when the circle is all black.
Period length
The full set of border lines divides the circle into 2k − 1 areas. Out of those, k have length (x − kz) each, and between them (except for zero) k − 1 areas have length 4z. Let's call the first ones "areas of type A" and the second ones "areas of type B".
It is easy to show that areas of type A change their color periodically. As we do the rounds of our process, first we turn them from black to white, one at a time, and then we turn them back from white to black, one at a time. Thus, all areas of type A are black only once every 2k rounds.
The same holds for areas of type B. But as there is only k − 1 of those, they are only all black once every 2(k − 1) rounds.
It follows that the entire circle is black once every 2k(k − 1) rounds. (Note that k and k − 1 are relatively prime.)
 1. In the task statement we just use some special values of x, but the proof and the algorithm work for all positive reals.


text:
Rain and soil moisture monitoring observations August 2017
Author: Liz Hamilton
Published: 04 Sep 2017
Recent rain and SMM observations:
Rainfall in August was generally above average, with large parts of the state exceeding 50 millimetres and some areas receiving in excess of 100 millimetres. There were some parts of the state that had between 25-50 millimetres of rain and Gippsland and the Milawa were some of those regions.
Soil moisture peaked in cropping paddocks on 21 August. All monitoring sites had a range of improvements in soil moisture during August (some being minor), but those with significant increases are highlighted with a red arrow in the speedo section. As listed in the previous SMM summary, it is always a positive sign to see soil moisture improving in August as crop biomass develops.Below is an example of what some of 14 speedos are showing us, for more information and to find a SMM site near you, email _EMAIL_ and subscribe to our newsletter.
Tags: Soil moisture


text:
About the Learning Studio
The Learning Studio (LS) an existing University-wide initiative is intended as a space where staff can learn together, growing into a collaborative learning community, based on their own professional practice. The community manifests its value in a sense of both producing something in common, and in engaging in interesting conversations, but the idea was that the interesting conversations will have some form of structure/goal, and that the community itself should produce the agenda for the conversations. Find out more and please join the forum debate here.
Back to Learning Studio landing page on process.arts


From Wikipedia, the free encyclopedia
Jump to: navigation, search
Town and union council
Country Pakistan
Region Balochistan
District Lasbela District
 - Total 10,000
Time zone PST (UTC+5)
Gadani is a coastal village of Lasbela District located in the southern part of Balochistan along the Arabian Sea, Pakistan. It is also a Union Council of Hub Tehsil[1] and is just a 1 hour drive away from Karachi, Sindh. The population of Gadani was estimated to be around 10,000 in 2005. More than 97% of the population is Muslim with a small Hindu minority. The majority of population speaks Balochi and there is a small Sindhi speaking minority. In Gadani majority of the population speaks a language named Balochi, this language is derived from Iran. They belong to Sanghur, Kurd, Sajdi, Muhammad Hasni, and Bezinjo tribes.
Many prehistoric shell-midden sites were discovered along the shores of a small bay, near Gadani. They are characterized of heaps of fragments of marine and mangrove shells among which are flint and jasper tools and stone querns. The first radiocarbon dates obtained from these middens indicate they result from the activity of people who settled along the coast both during the seventh and the fifth millennium before present.
Gadani Energy Park is an ambitious project of the new Pakistan Muslim League (Nawaz) Government (announced in August 2013) to establish 10 coal power plants of total capacity of 6,600 MW with technical and financial assistance from China. This will help in reducing the chronic power shortage problems being faced by Pakistan.[2]
Gadani Ship Breaking Yard[edit]
The world's third largest ship breaking yard, Gadani ship-breaking yard is located in Gadani. The yard consists of 132 ship-breaking plots located across a 10 km long beachfront at Gadani, Pakistan, about 50 kilometres northwest of Karachi.
Over 1 million tons of steel is scavenged per year, and much of it is sold domestically. In the 2009-2010 fiscal year, a record 107 ships, with a combined light displacement tonnage (LDT) of 852,022 tons, were broken at Gadani whereas in the previous 2008-2009 fiscal year, 86 ships, with a combined LDT of 778,598 tons, were turned into scrap.
Although, Gadani ranks as the world's third largest ship breaking yard after Alang and Chittagong in terms of volume, it is the world's leading ship breaking yard in terms of efficiency. At Gadani, a ship with 5,000 LDT is broken within 30 to 45 days, whereas in India and Bangladesh, it takes, on average, more than six months for breaking a vessel of the same size.
See also[edit]
External links[edit]
Coordinates: 25°07′10″N 66°43′55″E / 25.11944°N 66.73194°E / 25.11944; 66.73194


text:
Toggle Dark Mode
Apple stunned spectators at WWDC 2017 last month by introducing a bevy of new hardware products, including new Mac computers, new iPad Pro models, and perhaps most interesting of all, the company's first-ever, standalone Siri speaker, which has been dubbed HomePod. While Apple executives spent plenty of time outlining the HomePod's key specifications and real-world applications, however, very little about the $349 device's capabilities and underlying technology is known at this time. Fortunately, an Apple patent that was filed back in January of 2016, and published by the U.S. Patent & Trademark Office (USPTO) Thursday morning, might help us to connect some of the dots and in the process prove what a mighty, powerful, and technologically advanced speaker Apple has in store for this holiday season and beyond.
Apple's "Loudspeaker Equalizer" patent, No. 20170195790, outlines a technology called "smart awareness," which draws upon a variety of high-tech, smartphone-caliber components to help the device intelligently adapt to its imminent environment. Among these powerful HomePod components include an A8 SoC as a the central processor, a total of six microphones, seven tweeters, a dedicated, 4-inch subwoofer, and this so-called "spatial awareness" technology as the driving force behind what makes the HomePod truly shine amidst the rising sea of voice-driven virtual assistant offerings.
What Is Spatial Awareness?
Spatial awareness, as defined by Apple, is an invention that seeks to help solve one of the biggest problems with the current slate of wireless speakers on the market: sound variability, or the disparity in sound output as the direct result of where, in relation to the listener, the speaker is placed within a room. If you were to place a wireless speaker, for example, with the main subwoofer output butting-up against the wall, then you'd likely notice a significant amount of muddled and distorted acoustic output as the result of said power radiating right into the wall.
"The position of the listener's ears with respect to room boundaries will [also] affect the perceived frequency response in a similar manner," Apple writes.
Apple's solution to this problem is what gives the HomePod a true leg-up over its rivals, including the Google Home and Amazon Echo. By incorporating a total of six, active microphones around the inside and outside of the unit, Apple's A8 CPU is able to help equalize and filter sound based on a number of variables including speaker displacement, internal and external pressure levels, and data collected by the HomePod's hexagonal microphone array.
It's by comparing these internal and external microphone readings that Apple's device would then be able to "equalize and dynamically alter sound" based on where the speaker is placed. In contrast to other, less-expensive virtual assistant speakers, the technology outlined in Apple's patent is capable of intelligently and continuously adapting in real-time — rather than being calibrated every time.
The result? Remarkable audio output with advanced adaptation capabilities, which, as Apple boldly attested, will "reinvent the way we enjoy music."


text:
Stone Age groups' leg bones, spears reflect remarkably long treks
The Stone Age could just as easily be called the Roam Age.
Two new studies published February 27 in the Journal of Human Evolution advance the idea that ancient people and Neandertals walked or ran far greater distances than any human groups that followed, including more recent hunter-gatherers and today's long-distance runners. Fossils of humans and their beetle-browed evolutionary cousins display signs of extremely extended travel that occurred between roughly 120,000 and 10,000 years ago, Colin Shaw and Jay Stock, biological anthropologists at the University of Cambridge in England report in one of the studies.
Shaw and Stoc


Fennel documentation for v0.2.1
Online REPL using Fengari
Summary of user-visible changes
0.2.1 / 2019-01-22
0.2.0 / 2019-01-17
0.1.1 / 2018-12-05
0.1.0 / 2018-11-29
0.0.1 / 2016-08-14
Fennel Reference
These are all the special forms recognized by the Fennel compiler. It does not include built-in Lua functions; see the Lua reference manual for that.
fn function
Creates a function which binds the arguments given inside the square brackets. Will accept any number of arguments; ones in excess of the declared ones are ignored, and if not enough arguments are supplied to cover the declared ones, the remaining ones are nil.
Example: (fn pxy [x y] (print (+ x y)))
Giving it a name is optional; if one is provided it will be bound to it as a local. Even if you don't use it as an anonymous function, providing a name will cause your stack traces to be more readable, so it's recommended. Providing a name that's a table field will cause it to be inserted in a table instead of bound as a local.
lambda/λ arity-checked function
Creates a function like fn does, but throws an error at runtime if any of the listed arguments are nil, unless its identifier begins with?.
Example: (lambda [x?y z] (print (- x (* (or?y 1) z))))
The λ form is an alias for lambda and behaves identically.
partial partial application
Returns a new function which works like its first argument, but fills the first few arguments in place with the given ones. This is related to currying but different because calling it will call the underlying function instead of waiting till it has the "correct" number of args.
Example: (partial (fn [x y] (print (+ x y))) 2)
This example returns a function which will print a number that is 2 greater than the argument it is passed.
let scoped locals
Introduces a new scope in which a given set of local bindings are used.
Example: (let [x 89] (print (+ x 12)) -> 101
These locals cannot be changed with set but they can be shadowed by an inner let or local. Outside the body of the let, the bindings it introduces are no longer visible.
Any time you bind a local, you can destructure it if the value is a table or a function call which returns multiple values:
Example: (let [[a b c] [1 2 3]] (+ a b c)) -> 6
Example: (let [(x y z) (unpack [10 9 8])] (+ x y z)) -> 27
Example: (let [{:msg msg :val val} (returns-a-table)] (print msg) val)
local declare local
Introduces a new local inside an existing scope. Similar to let but without a body argument. Recommended for use at the top-level of a file for locals which will be used throughout the file.
Example: (local lume (require "lume"))
Supports destructuring and multiple-value binding.
match pattern matching
Evaluates its first argument, then searches thru the subsequent pattern/body clauses to find one where the pattern matches the value, and evaluates the corresponding body. Pattern matching can be thought of as a combination of destructuring and conditionals.
(match mytable
 59 :will-never-match-hopefully
 [9 q 5] (print :q q)
 [1 a b] (+ a b))
In the example above, we have a mytable value followed by three pattern/body clauses. The first clause will only match if mytable is 59. The second clause will match if mytable is a table with 9 as its first element and 5 as its third element; if it matches, then it evaluates (print :q q) with q bound to the second element of mytable. The final clause will only match if mytable has 1 as its first element; if so then it will add up the second and third elements.
Patterns can be tables, literal values, or symbols. If a symbol has already been bound, then the value is checked against the existing local's value, but if it's a new local then the symbol is bound to the value.
Tables can be nested, and they may be either sequential ([] style) or key/value ({} style) tables. Sequential tables will match if they have at least as many elements as the pattern. (To allow an element to be nil, use a symbol like?this.) Tables will never fail to match due to having too many elements.
(match mytable
 {:subtable [a b?c] :depth depth} (* b depth)
 _ :unknown)
You can also match against multiple return values using parentheses. (These cannot be nested, but they can contain tables.) This can be useful for error checking.
(match (io.open "/some/file")
 (nil msg) (report-error msg)
 f (read-file f))
Pattern matching performs unification, meaning that if x has an existing binding, clauses which attempt to bind it to a different value will not match:
(let [x 95]
 (match [52 85 95]
 [b a a] :no ; because a=85 and a=95
 [x y z] :no ; because x=95 and x=52
 [a b x] :yes)) ; a and b are fresh values while x=95 and x=95
There is a special case for _; it is never bound and always acts as a wildcard.
(Note that Lua also has "patterns" which are matched against strings similar to how regular expressions work in other languages; these are two distinct concepts with similar names.)
global set global variable
Sets a global variable to a new value. Note that there is no distinction between introducing a new global and changing the value of an existing one.
Example: (global prettyprint (fn [x] (print (view x))))
Supports destructuring and multiple-value binding.
var declare local variable
Introduces a new local inside an existing scope which may have its value changed. Identical to local apart from allowing set to work on it.
Example: (var x 83)
Supports destructuring and multiple-value binding.
set set local variable or table field
Changes the value of a variable introduced with var. Will not work on globals or let/local-bound locals. Can also be used to change a field of a table, even if the table is bound with let or local, provided the field is given at compile-time.
Example: (set x (+ x 91))
Example: (let [t {:a 4 :b 8}] (set t.a 2) t) -> {:a 2 :b 8}
Supports destructuring and multiple-value binding.
tset set table field
Set the field of a given table to a new value. The field name does not need to be known at compile-time. Works on any table, even those bound with local and let.
Example: (let [tbl {:d 32} field :d] (tset tbl field 19) tbl) -> {:d 19}
You can provide multiple successive field names to perform nested sets.
multiple value binding
In any of the above contexts where you can make a new binding, you can use multiple value binding. Otherwise you will only capture the first value.
Example: (let [x (values 1 2 3)] x) => 1
Example: (let [(file-handle message code) (io.open "foo.blah")] message) => "foo.blah: No such file or directory"
Example: (global (x-m x-e) (math.frexp 21)), {:m x-m :e m-e} => {:e 5 :m 0.65625}
Example: (do (local (_ _ z) (unpack [:a :b :c :d :e])), z) => c
Flow Control
if conditional
Checks a condition and evaluates a corresponding body. Accepts any number of condition/body pairs; if an odd number of arguments is given, the last value is treated as a catch-all "else". Similar to cond in other lisps.
(let [x (math.random 64)]
 (if (= 0 (% x 10))
 "multiple of ten"
 (= 0 (% x 2))
 "I dunno, something else"))
All values other than nil or false are treated as true.
when single side-effecting conditional
Takes a single condition and evaluates the rest as a body if it's not nil or false. As it always returns nil; this is intended for side-effects.
(when launch-missiles?
each general iteration
Run the body once for each value provided by the iterator. Commonly used with ipairs (for sequential tables) or pairs (for any table in undefined order) but can be used with any iterator.
(each [key value (pairs mytbl)]
 (print key (f value)))
Most iterators return two values, but each will bind any number.
for numeric loop
Counts a number from a start to stop point (inclusive), evaluating the body once for each value. Accepts an optional step.
(for [i 1 10 2]
 (print i))
This example will print all odd numbers under ten.
do evaluate


text:
The Research Institute of Pharmaceutical Sciences, or RIPS, was established in 1964 to discover and disseminate knowledge of natural drug products, develop and commercialize new products, improve public health and stimulate the economy. Research conducted by RIPS faculty and research scientists helps Mississippi industries to enhance their competitiveness and contributes to the economic development of the state.
RIPS comprises five centers:
The internationally-renowned National Center for Natural Products Research was founded in 1995 to research, develop and commercialize potentially useful natural products. Based at the University of Mississippi School of Pharmacy, NCNPR collaborates with academia, government and the pharmaceutical and agrochemical industries to create natural products that can be used to improve human health and agriculture as crops, pharmaceuticals, dietary supplements and agrochemicals.
The National Center for Cannabis Research and Education fosters and conducts scientific research, data analysis, education and training on the health effects of cannabis. NCCRE researchers and leaders will aid in policymaking and outreach as state programs emerge.
The Center for Clinical and Translational Science serves as a catalyst for the clinical and translational sciences between the University of Mississippi School of Pharmacy and UMMC. CCTS will facilitate the translation of basic research discoveries into clinically validated therapies to improve the health of populations in Mississippi and beyond.
The Center for Pharmaceutical Marketing and Management is a research center of excellence that advances research, teaching, and service in the areas of medication use and health outcomes, management of pharmacy organizations, and the marketing and utilization of appropriate medications in all segments of the healthcare industry.
The Pii Center conducts interdisciplinary drug and polymer research that provides end-stage pharmaceutical products directed at therapeutic conditions, vaccines, antidotes and wound care. Utilizing cutting edge thermal processing, the Pii Center collaborates with private industry, government and academia to develop new, improved and expanded drug delivery systems.


Missing Tooth (cam)
From Speeduino
Revision as of 22:37, 23 April 2019 by Josh (talk | contribs) (Text replacement - "_URL_ to "_URL_
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search
Overview
The missing tooth cam-speed trigger is a Speeduino innovation, that permits function similar to a dual-wheel setup, thereby allowing sequential or wasted spark operation from cam-mounted or distributor wheels. The operation is based on both Missing Tooth and Dual Wheel. It is suggested to read those sections first for familiarization as this section will only highlight the fundamental differences to those common decoders.
This decoder is comprised of a single cam-speed wheel in the same configuration as a crank-mounted missing-tooth wheel. The number of teeth must be evenly divisible into 720°. As it rotates at half crank speed, the sensor reads half the wheel teeth on each 360° crank revolution, and the remaining teeth on the next crank rotation. A single missing tooth will appear on only one of the two crank rotations, and is then used as a phase indicator, much as the dual-wheel system uses the cam signal.
Applications
Missing tooth cam or distributor wheels can be used with cam or distributor wheel modification or fabrication as no OEM systems use it originally. The wheel must have at least as many teeth as cylinders, not including the missing tooth. This generally requires double the number of teeth as cylinders or more. As many teeth, slots, or other readable features (sensor targets) as possible in the limited space is recommended in order to satisfy this requirement, and to maximize resolution. The sensor must be capable of reliably reading smaller or closely-spaced teeth.
Due to typically limited teeth, only half the teeth being read on each revolution, and the potential for reduced accuracy due to timing drive wear; the timing accuracy may be reduced in comparison to crank wheel systems. A figure of error cannot be predicted here as the wear or 'slop' of a given engine will be unique. However, it should be reasonable to assume the timing error will not exceed the accuracy of an OEM-equivalent cam-driven system such as typical distributor systems, or possibly better due to more sensor targets.
Tuner Studio Configuration
Fields:
 - Primary base teeth: This is the number of teeth the wheel would have if there were none missing, e.g. a 36-1 wheel has only 35 actual teeth, but you would enter 36 into this field.
 - Missing Teeth: The size of the 'gap' in the number of teeth. These missing teeth must be situated in a single block (ie there's only a single gap in the teeth). One missing tooth is recommended.
 - Trigger Angle: This is the angle in crank degrees AFTER TDC (ATDC) of the first tooth following the gap. This number ranges from -360° to +360°.
 - Cam Speed: Ensure this box is checked for this cam-speed system.
Timing Setting
The trigger angle is set in CRANK degrees, not cam.
Trigger Pattern


text:
Narrawallee Inlet Bird Walk
Grade and Distance: - 2.5km return (1.5hrs) - easy grade, formed walking path, sandy fire trail
Vegetation Types - coastal woodland, estuary
What to look for:
Common small birds along the track include fairy-wrens, White-throated Treecreepers, Varied Sittellas, Spotted Pardalotes, thornbills, Brown Gerygones, Leaden Flycatchers, Black-faced Monarchs and whistlers. Cicadabirds and Rose Robins have also been seen here. White-headed Pigeons, Brown Cuckoo-Doves and Satin Bowerbirds are all fairly common. At the inlet, look for cormorants, Azure and Sacred Kingfshers and a Striated Heron in the mangroves. White-breasted Woodswallows are common around the inlet during summer.
Downloadable PDF List for all bird species recorded on Birdata at Narrawallee Inlet
Follow Matron Porter Drive towards Narrawallee Inlet, turn left into Macleay Street just before the inlet and then left into Leo Drive. The walking track starts beside a little pump station between the houses and bushland. Follow the walking track and then turn right along the fre trail to the inlet.
This walk can also be found in the Shoalhaven Bird Walks brochure.
Links to all the self-guided Shoalhaven bird walks:


Term of the Moment
digital media player
Look Up Another Term
Definition: thunk
In a PC, to execute the instructions required to switch between segmented addressing of memory and flat addressing. A thunk typically occurs when a 16-bit application is running in a 32-bit address space, and its 16-bit segmented address must be converted into a full 32-bit flat address. On the other hand, if a 32-bit program calls a 16-bit DLL, then the thunk is in the opposite direction: from 32 bit to 16 bit.


text: Thermophysical properties of high-temperature materials are important from both the scientific and engineering points of view. This book includes the latest developments in the measurements of atomic structure, density, surface tension, viscosity, heat capacity, thermal and mass diffusivity, thermal conductivity, emissivity, and electrical conductivity of mainly metallic melts. High-temperature measurements are difficult due to high chemical reactivity and fluidity. Some distinctive inventions on the experimental techniques such as levitation technique combined with microgravity, synchrotron radiation or magnetic field enable high-precision measurements. This book is the perfect choice for specialists and nonspecialists eager to know the cutting-edge details in this field.


text:
STRANGE BUT TRUELarge snarge: Why snakes and rabbits hit airplanes
Q. What is "snarge,"and how are the good folks at the Smithsonian Institution's Feather Identification Laboratory working to make your next plane flight safer? –S. Sullenberger
A. Believe it or not, snarge is the bird goo left over from a collision with an airplane. And it's not just birds.
"We've had frogs, turtles, snakes, even a cat once struck at high altitudes," says the Smithsonian's Carla Dove. Birds like hawks and herons will occasionally drop their quarry into oncoming planes.
Recently, she sent a "snake" sample to the DNA lab, and it came back as rabbit.
"How do you explain to the Federal Aviation Administration (FAA) that we had a rabbit strike at 1,000 feet?" Dove asks.
It's of intense interest to both the FAA and the U.S. military to know what kinds of birds are smacking into the nation's airplanes. At the lab, technicians identify the snarge DNA, then enter the sequence into a national database.
Although most cases consist of feathers, many consist of a "paper towel swipe" of gooey bird fat, flesh bits, spores. Once the type of bird is identified, steps can be taken to avert future incidents, such as by altering flight paths and by engineering more bird-resistant planes.
As an example, jet engines must now be able to withstand the ingestion of an eight-pound waterfowl. "Of course, we're trying to improve aviation safety," says Dove, "but we're also helping to save the birds."
Q. Does lightning ever strike twice in the same place in the sense of successive holes-in-one struck by the same golfer? How about thrice? –J. Frost
A. Most remarkable was the performance of Norman Manley, who holed the seventh (330 yards) and eighth (290 yards) at California's Del Valle Country Club in 1964, says John Wesson in The Science of Golf. The thrice was achieved by Bob Taylor in 1974 on the Hunstanton Links course at Norfolk, England. He holed the 188-yard 16th-hole from the tee on the practice day of the competition, then did the same on both day 1 and day 2 of the competition proper– three successive holes-in-one on the same hole!
Record for the longest hole-in-one is tougher to assign, due to different conditions such as dog-legs and favorable slopes.
But longest success on a straight hole was in Omaha, Nebraska, in 1965 when Bob Mitera holed a 447-yard drive— helped, however, by a downhill slope. This record held until 2007 when Bret Melson aced the 448-yard, par 4 at the Ko'olau Golf Club in Oahu, Hawaii, "edging out Mitera by a massive one yard"!
Q. It's hard to sell the valiant human spirit short, especially when that spirit yearns to communicate under the most difficult of circumstances, such as the spirit of French journalist Jean-Dominique Bauby, who wrote the book The Diving Bell and the Butterfly, on which the movie was based. Explained one New York critic: The lightness of the butterfly symbolizes the persistence of Bauby's spirit, the heaviness of the bell his extreme physical difficulties. What difficulties? –S. Hawking
A. Bauby himself composed and dictated his memoir recounting the massive stroke that left him in a state known as "locked-in syndrome," mentally alert but deprived of speech and of all movement except for control of his left eyelid, says William Hanson in The Edge of Medicine.
Bauby painstakingly "wrote" by blinking his eyelid to select each letter as an assistant ran through a frequency-ordered alphabet and came to the correct letter.
He dictated the slim volume in the summer of 1996, averaging only a single word every two minutes. The following spring, ten days after the highly successful publication of his book, Bauby died.
Q. Folklore says lightning seeks out oak trees, and, surprisingly, a high percentage of trees shattered are oaks. So how does lightning pick them out from all the rest? –B. Franklin
A. Oaks aren't hit more, but their rough bark traps rainwater and keeps the lower trunk dry, especially early in a storm, says Jearl Walker in Flying Circus of Physics.
Smooth-barked trees get drenched faster, top to bottom, so the lightning descends harmlessly through the water sheath into the ground. For oaks, the current more often enters the tree, heats the sap and blows the trunk apart.
Send strange questions to brothers Bill and Rich at _EMAIL_.


cyrrhizic acid as stabilizer and evaluated in vitro. Methods: Pue-NE was prepared by high-speed shear and high-pressure homogenization method, and further combined with freeze-drying method to prepare Pue-NE-LP. Taking the average particle size and polydispersity index (PDI) as the evaluation indexes, the optimal prescription and process parameters of this experiment were screened out through a single factor test. The prepared Pue-NE-LP was characterized by physicochemical properties and dissolution in vitro. Results: The average particle size and PDI of Pue-NE-LP prepared with 5% glyceryl caprylate as oil phase, 2.0 mg/mL glycyrrhizic acid as stabilizer, and 7% glucose as lyophilization protectant was (215.1 ± 0.7) nm and (0.133 ± 0.024), respectively. Scanning electron microscopy showed that Pue-NE-LP was irregularly small and uniform in size; X-ray diffraction showed that Pue-NE-LP existed in an amorphous state. In vitro release results showed that the dissolution rate of Pue-NE-LP was significantly higher than the physical mixture. Conclusion: Pue-NE-LP prepared with natural surfactant glycyrrhizic acid as a stabilizer is not only simple to prepare, but also can significantly improve the solubility and bioavailability of puerarin. It provides a reference for the multiple development of Pue-NE formulations.
7.
Article in Chinese | WPRIM | ID: wpr-846355
ABSTRACT
Objective: Puerarin nanoemulsion (Pue-NE) was prepared with glycyrrhizic acid as a natural stabilizer, and its release characteristics in vitro were investigated. Methods: Data processing was performed using particle size and polydispersity index (PDI) as independent variables, and using the overall desirability (OD) as the evaluation index. The central composite design-response surface method was used to optimize the prescription, and the physical and chemical properties and release characteristics of Pue-NE prepared by the optimal prescription were investigated. Results: The best prescription for Pue-NE is puerarin at a concentration of 5.0 mg/mL, glycyrrhizic acid at a concentration of 1.75 mg/mL, and caprylic glyceride in an amount of 3.5 mL. The average particle size of the nanoemulsion is (184.5 ± 0.8) nm, the PDI is 0.088 ± 0.002, the zeta potential is (10.56 ± 0.35) mv, the conductivity is (98.3 ± 0.4) μs/cm, pH is 6.750 ± 0.005, solubility (4.970 ± 0.008) mg/mL, drug loading is (99.4 ± 0.2)%, turbidity (24.3 ± 1.0) cm-1 (n = 3). It was identified as O/W emulsion by dyeing method. TEM scanning results show that the droplets are spherical and uniform in size and the stability results showed that Pue-NE has good storage stability at 25 ℃. In vitro release results showed that Pue-NE has the greatest release in phosphate buffered pH 6.8 within 24 hours. Conclusion: The preparation of Pue-NE with glycyrrhizic acid as a natural stabilizer is not only simple and convenient, but also can effectively replace the use of traditional chemical synthetic stabilizers and improve the solubility of puerarin.
8.
Journal of Integrative Medicine ; (12): 229-241, 2020.
Article in English | WPRIM | ID: wpr-829101
ABSTRACT
OBJECTIVE@#Lung-toxin Dispelling Formula No. 1, referred to as Respiratory Detox Shot (RDS), was developed based on a classical prescription of traditional Chinese medicine (TCM) and the theoretical understanding of herbal properties within TCM. Therapeutic benefits of using RDS for both disease control and prevention, in the effort to contain the coronavirus disease 2019 (COVID-19), have been shown. However, the biochemically active constituents of RDS and their mechanisms of action are still unclear. The goal of the present study is to clarify the material foundation and action mechanism of RDS.@*METHODS@#To conduct an analysis of RDS, an integrative analytical platform was constructed, including target prediction, protein-protein interaction (PPI) network, and cluster analysis; further, the hub genes involved in the disease-related pathways were identified, and the their corresponding compounds were used for in vitro validation of molecular docking predictions. The presence of these validated compounds was also measured in samples of the RDS formula to quantify the abundance of the biochemically active constituents. In our network pharmacological study, a total of 26 bioinformatic programs and databases were used, and six networks, covering the entire Zang-fu viscera, were constructed to comprehensively analyze the intricate connections among the compounds-targets-disease pathways-meridians of RDS.@*RESULTS@#For all 1071 known chemical constituents of the nine ingredients in RDS, identified from established TCM databases, 157 passed drug-likeness screening and led to 339 predicted targets in the constituent-target network. Forty-two hub genes with core regulatory effects were extracted from the PPI network, and 134 compounds and 29 crucial disease pathways were implicated in the target-constituent-disease network. Twelve disease pathways attributed to the Lung-Large Intestine meridians, with six and five attributed to the Kidney-Urinary Bladder and Stomach-Spleen meridians, respectively. One-hundred and eighteen candidate constituents showed a high binding affinity with SARS-coronavirus-2 3-chymotrypsin-like protease (3CL), as indicated by molecular docking using computational pattern recognition. The in vitro activity of 22 chemical constituents of RDS was validated using the 3CL inhibition assay. Finally, using liquid chromatography mass spectrometry in data-independent analysis mode, the presence of seven out of these 22 constituents was confirmed and validated in an aqueous decoction of RDS, using reference standards in both non-targeted and targeted approaches.@*CONCLUSION@#RDS acts primarily in the Lung-Large Intestine, Kidney-Urinary Bladder and Stomach-Spleen meridians, with other Zang-fu viscera strategically covered by all nine ingredients. In the context of TCM meridian theory, the multiple components and targets of RDS contribute to RDS's dual effects of health-strengthening and pathogen-eliminating. This results in general therapeutic effects for early COVID-19 control and prevention.
Subject(s)
Antiviral Agents , Chemistry , Therapeutic Uses , Betacoronavirus , Chemistry , Coronavirus Infections , Drug Therapy , Virology , Cysteine Endopeptidases , Chemistry , Drugs, Chinese Herbal , Chemistry , Therapeutic Uses , Humans , Mass Spectrometry , Medicine, Chinese Traditional , Molecular Docking Simulation , Pandemics , Pneumonia, Viral , Drug Therapy , Virology , Protein Interaction Maps , Viral Nonstructural Proteins , Chemistry
9.
Article in Chinese | WPRIM | ID: wpr-824946
ABSTRACT
Objective: By observing the effects of electroacupuncture (EA) on the apoptosis of conjunctival cells of rabbits with dry eye syndrome (DES) and the expressions of apoptosis-related proteins Caspase-3, Fas and Bcl-2, to discuss the mechanism of EA in the treatment of DES from the perspective of cell apoptosis. Methods: Male New Zealand rabbits were randomly divided into a normal group (NG), a model group (MG), an EA group (EAG) and a sham EA group (SEAG). DES rabbit model was developed by eye drop of 0.1％ benzalkonium chloride. The rabbit tear secretion and tear film break-up time (BUT) were measured; terminal deoxynucleotidyl transferase- mediated dUTP nick end labeling (TUNEL) assay was used to detect the apoptosis of conjunctival cells; the expressions of Caspase-3, Fas and Bcl-2 proteins in conjunctival cells were detected by immunohistochemistry. Results: Compared with the NG, the rabbit tear secretion decreased and the BUT was shortened in the MG (both P<0.01); compared with the MG and the SEAG, the rabbit tear secretion increased and the BUT was prolonged in the EAG (all P<0.05). Compared with the NG, the apoptosis of rabbit conjunctival cells increased (P<0.01), the expressions of Caspase-3 and Fas proteins increased (both P<0.05), and the expression of Bcl-2 protein decreased (P<0.01) in the MG; compared with the MG and the SEAG, the apoptosis of rabbit conjunctival cells decreased (both P<0.01), the expressions of Caspase-3 and Fas proteins decreased (all P<0.05), and the expression of Bcl-2 protein increased (both P<


text:
Chapter V-G. Lectern or Place from Which the Word of God is Proclaimed
272. The dignity of the word of God requires the church to have a place that is suitable for proclamation of the word and is a natural focal point for the people during the Liturgy of the Word.
As a rule the lectern or ambo should be stationary, not simply a movable stand. In keeping with the structure of each church, it must be so placed that the ministers may be easily seen and heard by the faithful.
The readings, responsorial psalm, and the Easter Proclamation (Exsultet) are proclaimed from the lectern; it may be used also for the homily and general intercessions (prayer of the faithful).
It is better for the commentator, cantor, or choir director not to use the lectern.


What is Checkology?
Providing valuable skills
Checkology gives you the habits of mind and tools to evaluate and interpret information. And you gain an understanding of the importance of the watchdog role of the press.
Experts lead the way
Top journalists and digital media experts anchor the platform's interactive lessons.
Featuring real-world examples from social media and news sites, these e-learning experiences resonate with learners of all ages, helping them to identify credible information, seek out reliable sources and know what to trust, what to dismiss and what to debunk.
Checkology features
 1. Evaluation
 Educators can see and access all work that a student submits through our lightweight learning management system (LMS).
 2. Word Wall
 The Word Wall offers students quick access to a glossary of news literacy terms.
 3. Co-teachers
 Educators can assign a co-teacher to each section of students, enabling that teacher to also access and evaluate students' work.
 4. Discuss Wall
 On this optional classroom discussion wall, students can respond to prompts created by their educator.
 5. Messaging
 Educators can send three types of messages to students within the platform: announcements, text-response and multiple choice.
Checkology features
For Everyone
For Educators
Learn how to
categorize information.
make and critique news judgments.
explore how the press and ordinary people can each act as watchdogs.
detect and categorize misinformation.
interpret and apply the First Amendment.
(Only available for student learners.)
compare the ways that countries protect or restrict press freedom.
(Only available for student learners.)
identify logical fallacies and evaluate arguments.
(Only available for student learners.)
investigate the impact of personalization algorithms.
(Only available for student learners.)
"I have really loved all of the resources I've gained and the knowledge my students are walking away with... and the skills that they're able to apply to their own reading and consumption of media."
Nicole Finnesand, high school teacher, Colton, South Dakota
Help make the world more news-literate!


text:
U-Logs is a global RFID logistics management system that is being used as a solution for both retailers and ready-made garment manufacturers for years. It helps companies to save manpower and time, resulting with decreased costs and increased sustainability. This system consists of an RFID device, Software and Web Portal.
With this system, retailers can start Supply Chain automation from the manufacturer's factory, enabling real time data sharing, thus total supply chain visibility.
1 Hardware: U-Logs's hardware portfolio has rich variable options as solutions to different type of products. They are being used in many warehouses, factories and logistics centers since last decade to provide live data and supply chain visibility.
2 Software: U-Logs's software was developed by channeling years of experience in textile industry and requirements of modern supply chain visibility to a cloud based solution. It gathers the information from the RFID Tagged Items and sends it to the cloud server where that information becomes a usable data for the retailer and manufacturer.