Jakub Husník

Jakub Husník (29 March 1837, in Vejprnice, near Pilsen – 26 March 1916, in Prague) was a Czech painter, art teacher and inventor of the improved photolithography method.

Life
Husník was one of the ten children of Foersters. After the attending schools in Hlavatce and Benešov, he completed the Prager six-form high school. In 1853, he entered into the painter academy where he met Karel Klíč. He studied in Antwerp with professor Joseph Henri François van Lerius. After his return, he was active in the church of Uhrínevs. In 1863, he became a teacher at the High School in Tábor. In 1877, he was appointed as the art professor at the material High School. After one year, he also opened an independent workshop for lithography.

Research
Together with professor Schwarz, he examined the "wet process" when developing photographs. He first discovered the "zweitonige photograph". In 1893, he perfected the three-colored reproduction for the printing and announced first patents.

Works
Husník wrote specialized books concerning his inventions.

Honours and memberships
In 1907, Husník became an honorary member of the photographic society in Vienna and Berlin.

Category:1837 births
Category:1916 deaths
Category:Czech inventors
Category:19th-century Czech painters
Category:Czech male painters
Category:20th-century Czech painters


1992 European Weightlifting Championships

The 1992 European Weightlifting Championships were held in Szekszárd, Hungary from April 21 to April 26, 1992. It was the 71st edition of the event. There were a total number of 149 athletes competing, from 30 nations. The women competition were held in Loures, Portugal. It was the 5th event for the women.

Medal summary

Men

Medals tables
Ranking by Big (Total result) medals

References
Weightlifting Database

Category:European Weightlifting Championships
European Weightlifting Championships
European Weightlifting Championships
Category:International weightlifting competitions hosted by Hungary


Danny Putnam

Daniel Chris "Danny" Putnam (born September 17, 1982) is an American former professional baseball outfielder. He played in Major League Baseball (MLB) for the Oakland Athletics.

Career
As a student at Rancho Bernardo High School in 2001, he was named the USA Today California High School Player of the Year. He attended Stanford University, and in 2002 he played collegiate summer baseball with the Hyannis Mets of the Cape Cod Baseball League. He was selected by the A's in the first round of the 2004 MLB Draft.

He played parts of three seasons in the minors before being called up in April . Putnam returned to the minors in May 2007 when Milton Bradley returned from an injury.

He was designated for assignment on January 11, 2008, and started the year playing for their Triple-A affiliate, the Sacramento River Cats.

In 2010 Putnam played for the Bridgeport Bluefish of the independent Atlantic League.

References

External links

Category:1982 births
Category:Living people
Category:People from St. Clair County, Illinois
Category:Baseball players from Illinois
Category:Major League Baseball outfielders
Category:Oakland Athletics players
Category:Stanford Cardinal baseball players
Category:Hyannis Harbor Hawks players
Category:Vancouver Canadians players
Category:Kane County Cougars players
Category:Stockton Ports players
Category:Midland RockHounds players
Category:Sacramento River Cats players
Category:Arizona League Athletics players
Category:Portland Beavers players
Category:Bridgeport Bluefish players
Category:Baseball players at the 2003 Pan American Games
Category:Pan American Games silver medalists for the United States
Category:Pan American Games medalists in baseball


2016 Pakatan Harapan alternative federal budget

The Malaysian alternative federal budget for the 2016 fiscal year was launched by Pakatan Harapan on 21 October 2015, two days before the Malaysian Budget Day, as a response to the government's federal budget.

Areas of direction
Some of the key items in the alternative budget were:
 Implementing the capital gains tax since this is also being implemented in 127 countries, including all European countries which are part of the OECD.
 Implementing the inheritance tax since many OECD members already implemented.
 Restructuring of 1Malaysia Development Berhad (1MDB) by putting the firm into administration and prosecuting wrongdoers.
 Separation of Prime Minister and Finance Minister portfolios to avoid excessive concentration of power held by one individual.
 Support extension of Zeti Akhtar Aziz's term as Bank Negara Malaysia governor by two more years.
 For a short term, keeping Goods and Services Tax (GST) system by zero-rating all items to mitigate inflation.
 To set up a petroleum endowment fund for East Malaysians.
 The Kuala Lumpur-Singapore high speed rail (HSR) project funds will instead be reallocated to building a rail network in Sabah and Sarawak.
 Offset the loss of GST income by making MYR30 billion in savings by stamping out "wastage and corruption", and also by shutting down several state-linked corporations.
 Reducing PETRONAS dividend to MYR20 billion.
 Revamping cash handouts such as Bantuan Rakyat 1Malaysia (BR1M) to be conditional on employment and school attendance; the low-income parents must work and send their children to schools.
 Focusing more on agriculture because the country’s agricultural policies were “backward, if compared with other countries”; it is necessary to give the subsidies directly to the farmers and also provide a subsidy for the price of rice.
 Parliamentary oversight of sovereign wealth funds for greater accountability, accountability and full independence of regulators which include the Malaysian Anti-Corruption Commission (MACC), Attorney-General of Malaysia, Bank Negara Malaysia and Parliament of Malaysia.
 Focus in bridging the economic activities' gap in Peninsular Malaysia and those in Sabah and Sarawak.

Total revenues and spending

Revenues

(In million MYR)

Expenditures by object
These tables are in million MYR.

Reactions

See also
 2016 Malaysian federal budget

References

Category:Malaysian budgets
Category:13th Parliament of Malaysia
Category:2015 in Malaysian politics
Pakatan Harapan alternative federal
Category:2015 in Malaysian law


1975 Major League Baseball season

The 1975 Major League Baseball season saw Frank Robinson become the first black manager in the Major Leagues. He managed the Cleveland Indians.

At the All-Star Break, there were discussions of Bowie Kuhn's reappointment. Charlie Finley, New York owner George Steinbrenner and Baltimore owner Jerry Hoffberger were part of a group that wanted him gone. Finley was trying to convince the new owner of the Texas Rangers Brad Corbett that MLB needed a more dynamic commissioner. During the vote, Baltimore and New York decided to vote in favour of the commissioner's reappointment. In addition, there were discussions of expansion for 1977, with Seattle and Washington, D.C. as the proposed cities for expansion.

Regular season standings

American League

National League

Awards and honors
Baseball Hall of Fame
Earl Averill
Bucky Harris
Billy Herman
Judy Johnson
Ralph Kiner
Most Valuable Player
Fred Lynn (AL) Boston Red Sox
Joe Morgan (NL) Cincinnati Reds
Cy Young Award
Jim Palmer (AL) Baltimore Orioles
Tom Seaver (NL) New York Mets
Rookie of the Year
Fred Lynn (AL) Boston Red Sox
Andre Dawson (NL) Montreal Expos
Gold Glove Award
George Scott (1B) (AL)
Bobby Grich (2B) (AL)
Brooks Robinson (3B) (AL)
Mark Belanger (SS) (AL)
Paul Blair (OF) (AL)
Fred Lynn (OF) (AL)
Joe Rudi (OF) (AL)
Thurman Munson (C) (AL)
Jim Kaat (P) (AL)

Postseason

Statistical leaders

Notable events
 August 14 - Atlanta Braves pitcher Phil Niekro hits the only triple of his Major League career, off the pitching of Lynn McGlothen of the St Louis Cardinals.

References

External links
1975 Major League Baseball season schedule at Baseball Reference

Category:Major League Baseball seasons


Facelina dubia

Facelina dubia is a species of sea slug, an aeolid nudibranch, a marine gastropod mollusc in the family Facelinidae.

Distribution
This species has been reported from County Cork, Ireland south to the Mediterranean Sea.

References

Category:Facelinidae
Category:Gastropods described in 1948
Category:Taxa named by Alice Pruvot-Fol


Orders, decorations, and medals of Slovenia

The decorations () for citizens who do great deeds for, or on behalf of, the country.

Orders of Freedom of the Republic of Slovenia
The Orders of Freedom of the Republic of Slovenia () are a special class of decorations "for services rendered in the defence of freedom and assertion of the sovereignty of the Republic of Slovenia or only in connection with the said acts related to the gaining of independence." They are the highest civilian award given by the government of Slovenia. A majority of recipients of the Orders of Freedom were directly involved in Slovenia's struggle for independence from Yugoslavia, including the Ten-Day War which established their independence.

There are three levels in the Orders of Freedom:
The Golden Order of Freedom () is symbolised with a medal on a necklace. The medal is a gold version of the Order of Freedom medallion, on a blue ribbon necklace with tricolor stripes. The bar pin is also gold.
The Silver Order of Freedom () is symbolised the same way as the Order of Freedom, but the medallion and bar pins are silver.
The Order of Freedom () is symbolised by a small crystal medallion with a center medal in the tricolors of the Slovenian flag. Recipients also receive an aluminum bar pin with the Slovenian tricolors in the center.

The Orders of Freedom were established by the Orders of Freedom of the Republic of Slovenia Act in 1992.

Other Orders and Medals
The other orders and medals () were established to honor works that advance Slovenia as a nation. With the exception of the highest honor, the Order of Exceptional Merits, they are split into three different categories, with a different medal design for each category: civil field, diplomatic and international field, and military or security field. These decorations were established by the Decorations of the Republic of Slovenia Act, instituted in 2004. Except for the Order of Exceptional Merits each field has a slightly different medal design.

The Order for Exceptional Merits () is "for exceptional work and services rendered in advancing the sovereignty, prosperity, renown and progress of Slovenia." It is a white, blue and gold medal with a red dot at the center, suspended from a gold and red ribbon pin. It includes a gold and red bar pin.
The Golden Order for Merits () is "for exceptional merits accomplished for Slovenia." Its medal is the same as the Order of Exceptional Merits, but is suspended on a yellow ribbon pin. It includes a yellow bar pin in addition.
The Silver Order for Merits () is "for exceptional work and services rendered in the security, defence and protection of the Republic of Slovenia and for international cooperation in these fields." Its medal is similar to the Golden Order, but has silver backing and a silver center shield, and is suspended from a blue ribbon pin. It includes a blue bar pin.
The Order for Merits () is "for services accomplished for the Republic of Slovenia in other fields." Its medal is similar to the Silver Order, but lacks the silver backing.
The Medal for Merits () is "for especially remarkable achievements and results in the fields marking an important contribution to the development and international standing of the Republic of Slovenia." Its medal is white with a blue backing and silver center shield, suspended on a blue ribbon pin with three horizontal gold stripes. Its bar pin is blue with three vertical gold stripes.
The Medal for Valour () is "for personal valour and self-sacrifice in saving human lives and material goods." Its medal and bar pin are similar to the Medal for Merits, but have only two gold stripes. It is the only honor that does not have a provision for being conferred upon foreign nationals or organisations.
The Medal for Honourable Action () is "for exceptional actions worthy of particular distinction." Its medal is the reverse colors of the Medal for Merits/Valour, and the ribbon and bar pin have only one gold stripe.

External links
Decorations from the Official Website of the President of the Republic of Slovenia (English version)


Langlitinden

Langlitinden is the highest mountain on the island of Andørja and is also the highest mountain on any Norwegian island (except Beerenberg, Jan Mayen). It is located on the northeastern part of the island in the municipality of Ibestad in Troms og Finnmark county, Norway, just to the south of the Mjøsund Bridge and just northwest of the shore of the Astafjorden. The mountain is  tall.

References

Category:Mountains of Troms og Finnmark
Category:Ibestad


Los Pinos Peak

Los Pinos Peak is a  summit in the Santa Ana Mountains in Orange County, California, about  east of Rancho Santa Margarita. Los Pinos is the southernmost peak above  in the Santa Anas, and provides extensive views south towards San Diego and the Pacific Ocean as well as views (on clear days) of the San Jacinto Mountains and San Bernardino Mountains in the east. The summit rises rather prominently above the main crest of the Santa Anas and is conspicuously visible from much of southern Orange County, although its actual topographic prominence is only about .

The peak is situated in the Cleveland National Forest and is accessible by the Main Divide Road (a fire road); the Trabuco Canyon Trail, which begins near Trabuco Creek, and the Los Pinos Peak Trail, which begins in Hot Springs Canyon (near San Juan Canyon, San Juan Creek and the Ortega Highway (State Route 74).

References

Category:Mountains of Orange County, California
Category:Mountains of Southern California


Rhodobates canariensis

Rhodobates canariensis is a species of moth of the family Tineidae. It was described by Petersen and Gaedike in 1979. It is found on the Canary Islands.

The wingspan is about 20 mm.

References

Category:Moths described in 1979
Category:Myrmecozelinae
Category:Insects of the Canary Islands


Tyrique Lake

Tyrique Lake is an Anguillan footballer who plays college soccer for Longwood University as a midfielder.

Early and personal life
Lake was born in Saint Thomas, U.S. Virgin Islands,

Career
Lake attended Fayetteville High School, where he was named to the All State, All Conference and All Star Soccer teams. He then attended Crowder College. After spending his freshman and sophomore years there, Lake transferred to Longwood University.

Lake made his senior international debut on 18 November 2018 in a 1-1 away draw with the Bahamas during CONCACAF Nations League qualifying.

Career statistics

International

References

External links
Tyrique Lake at Crowder College Roughriders Official Website
Tyrique Lake at Longwood University Lancers Official Website

Category:Year of birth missing (living people)
Category:Living people
Category:Anguillan footballers
Category:Anguilla international footballers
Category:Association football midfielders
Category:People from Saint Thomas, U.S. Virgin Islands


Suchiapa River

The Suchiapa River is a river in the state of Chiapas, Mexico.

See also
List of rivers of Mexico

References
Atlas of Mexico, 1975 (http://www.lib.utexas.edu/maps/atlas_mexico/river_basins.jpg).
The Prentice Hall American World Atlas, 1984.
Rand McNally, The New International Atlas, 1993.

Category:Rivers of Mexico


Battle of Timbuktu

The Battle of Timbuktu occurred in Timbuktu, Mali, in March 2013, between Islamist groups and Mali government forces supported by France.

On the night of 20–21 March, a group of Islamist militants tried to infiltrate the airport. A car with armed men also tried to break into the city; however, French and Malian forces pushed them back.

Attack
The city of Timbuktu was guarded by the Malian army while about 150 French soldiers guarded the airport. Then, about 50 to 100 Islamists launched an attack from Bamba, west of Bourem, at March 20 at 10:19 pm. A suicide car bomber exploded himself on a road south of the Timbuktu airport. Camouflaged in the colors of the Malian army, the vehicle arrived near a checkpoint held by Malian soldiers. The attack killed one and wounded another two Malians. Shortly after, some 30 jihadists crossed the Mouamar Gaddafi canal and attacked the airport from the east. The shooting lasted several hours before dying out in the evening. Meanwhile, Malian troops were coming out of Timbuktu to help the French, but they crossed another group of jihadists. Three Malians were wounded from friendly fire. The French then asked the Malians to retreat to avoid further fratricide. At 1 am, the French bombarded Jihadist positions, leading them to retreat. The jihadists returned to the offensive the next morning, but after an hour of fighting, and after two failed suicide attacks, they retreated. The attack was later claimed by MOJAO, but the French claimed that AQIM  participated as well. Eight Malians were wounded and one killed, with the French giving estimates of 5 to 11 Jihadist killed.

See also
 Second Battle of Timbuktu

References

Category:Conflicts in 2013
Category:2013 in Mali
Battle
Category:Battles involving France
Category:Mali War
Category:March 2013 events in Africa


GLI1

Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene.  It was originally isolated from human glioblastoma cells.

Function
The Gli proteins are the effectors of Hedgehog (Hh) signaling and have been shown to be involved in cell fate determination, proliferation and patterning in many cell types and most organs during embryo development. In the developing spinal cord the target genes of Gli proteins, that are themselves transcription factors, are arranged into a complex gene regulatory network that translates the extracellular concentration gradient of Sonic hedgehog into different cell fates along the dorsoventral axis.

The Gli transcription factors activate/inhibit transcription by binding to Gli responsive genes and by interacting with the transcription complex.  The Gli transcription factors have DNA binding zinc finger domains which bind to consensus sequences on their target genes to initiate or suppress transcription.  Yoon showed that mutating the Gli zinc finger domain inhibited the proteins effect proving its role as a transcription factor.  Gli proteins have an 18-amino acid region highly similar to the α-helical herpes simplex viral protein 16 activation domain.  This domain contains a consensus recognition element for the human TFIID TATA box-binding protein associated factor TAFII31. Other proteins such as Missing in Metastasis (MIM/BEG4) have been shown to potentiate the effects of the Gli transcription factors on target gene transcription.  Gli and MIM have been shown to act synergistically to induce epidermal growth and MIM + Gli1 overexpressing grafts show similar growth patterns to Shh grafts.

Gli family
There are three members of the family; Gli1, Gli2 and Gli3 which are all transcription factors mediating the Hh pathway.  The GLI1, GLI2, and GLI3 genes encode transcription factors which all contain conserved tandem C2-H2 zinc finger domains and a consensus histidine/cysteine linker sequence between zinc fingers.  This Gli motif is related to those of Kruppel which is a Drosophila segmentation gene of the gap class. In transgenic mice, mutant Gli1 lacking the zinc fingers does not induce Sonic Hedgehog (Shh) targets. The conserved stretch of 9 amino acids connects the C-terminal histidine of one finger to the N-terminal cysteine of the next. The GLI consensus finger amino acid sequence is [Y/F]JXCX3GCX3[F/Y]X5LX2HX4H[T/S]GEKP.  The Gli1 and Gli2 protein zinc finger DNA binding domain have been shown to bind to the DNA consensus GLI binding site GACCACCCA.

Gli Proteins transcriptional regulation is tissue specific for many targets.  For example, Gli1 in primary keratinocytes upregulates FOXM1 whereas in mesenchymal C3H10T1/2 cells it has been shown to upregulate platelet-derived growth factor receptor PDGFRa.

Human Gli1 encodes a transcription activator involved in development that is a known oncogene.  It has been found that N-terminal regions of Gli1 recruit histone deacetylase complexes via SuFu, which are involved in DNA folding in chromosomes.  This may negatively regulate transcription indicating Gli1 could act as transcriptional inhibitor as well as an activator. The human GLI1 promoter region is regulated by a 1.4 kb 5’ region including a 5’ flanking sequence, an untranslated exon and 425bp of the first intron.  Numerous proteins such as Sp1, USF1, USF2, and Twist are also involved  in Gli1 promoter regulation.  During mouse embryo development Gli1 expression can be detected in the gut mesoderm, ventral neural tube, ependymal layer of the spinal cord, forebrain, midbrain, cerebellum, and in sites of endochondral bone formation.  Some of the downstream gene targets of human Gli1 include regulators of the cell cycle and apoptosis such as cyclin D2 and plakoglobin respectively.   Gli1 also upregulates FoxM1 in BCC.  Gli1 expression can also mimic Shh expression in certain cell types.

Isolation
GLI1 was originally isolated from a glioma tumour and has been found to be up regulated in many tumors including muscle, brain and skin tumors such as Basal cell carcinoma (BCC).
DNA copy-number alterations that contribute to increased conversion of the oncogenes Gli1–3 into transcriptional activators by the Hedgehog signaling pathway are included in a genome-wide pattern, which was found to be correlated with an astrocytoma patient’s outcome.
Shh and the Gli genes are normally expressed in hair follicles, and skin tumours expressing Gli1 may arise from hair follicles.  The level of Gli1 expression correlates with the tumor grade in bone and soft tissue sarcomas.   Transgenic mice and frogs overexpressing Gli1 develop BCC like tumours as well as other hair follicle-derived neoplasias, such as trichoepitheliomas, cylindromas, and trichoblastomas.  Expression of Gli1 in the embryonic frog epidermis results in the development of tumours that express endogenous Gli1. This suggests that overexpressed Gli1 alone is probably sufficient for tumour development  Mutations leading to the expression of Gli1 in basal cells are thus predicted to induce BCC formation.

Interactions
GLI1 has been shown to interact with:
 SAP18,
 STK36,
 SUFU,  and
 ZIC1.

References

External links

Category:Proteins
Category:Transcription factors


Rashed Al Hajri

Rashed Al Hajri (Arabic:راشد الهاجري) (born 25 April 1995) is a Emirati footballer. He currently plays for Ajman as a forward .

External links

References

Category:Emirati footballers
Category:1995 births
Category:Living people
Category:Al-Shaab CSC players
Category:Al-Wasl F.C. players
Category:Ajman Club players
Category:UAE Division 1 players
Category:UAE Pro League players
Category:Association football forwards


Tokyo (Juju song)

is a song recorded by Japanese singer Juju, from her seventh studio album I. It was released as the album's fifth single by Onenation on January 24, 2018. The song was co-written by Yū Arakaki and Masaki Yasujima of the music duo Akidasu, credited as R-Y's, and Tomoko, and composed by the former. The track was arranged and produced by Koichi Tsutaya. "Tokyo" is the theme song to the film Inori no Maku ga Oriru Toki (2018), the last chapter of the Shinzanmono series starring Hiroshi Abe, based on the novel of the same name by Keigo Higashino. The first pressing of the CD single comes with a DVD including a selection of live performances from Juju's Juju Hall Tour 2016 What You Want concert tour.

Background
"Tokyo" was released merely three months following Juju's previous single, "Iiwake". The song's music video features actress Moeka Hoshi and was directed by Kentarō Hagiwara of Tokyo Ghoul fame. Koichi Tsutaya, who produced the song, stated about working with Juju that she stands out in the current Japanese music scene by being one of the few singers to put out varied quality adult contemporary music.

Chart performance
"Tokyo" debuted at number 17 on the Oricon Singles Chart, with 4,000 copies sold in its first week. The song also charted on the Oricon Digital Singles Chart, debuting at number 4 and selling 18,000 downloads. "Tokyo" peaked at number 6 on Billboard Japan's Hot 100 chart.

Track listing

Charts

Sales

|-
! scope="row"| Japan (RIAJ)
|
| 9,000
|-
! scope="row"| Japan (RIAJ)
|
| 60,000 (digital)
|-

References

Category:2018 songs
Category:2018 singles
Category:Songs written for films
Category:Juju (singer) songs
Category:Onenation singles


Cagdanao

Cagdanao is an island in the province of Palawan in the Philippines. The island is located  east from the town of Taytay in northern Palawan and  from El Nido Airport.

The island is surrounded with a coral reef, from shallow coral gardens to deep drop-offs on the north side. Cagdanao Island offers a variety of diving sites around the island. On the island, beaches frontage of  with white sand and a  of flat land that extends back to the edge of the hills. Hilly elevation with vegetation like palms, loamy and forest soil sandy.

Access to the island is mainly from Palawan, via a 40-minute sail with a speedboat. Cagdanao Island is a popular site for snorkeling and scuba diving in and around its coral reef. Damselfish (Pomacentridae), gobies (Gobiidae) and wrasses (Labridae) are the most abundant fish families.

A beach resort called Cagdanao Island Beach Resort is situated on the island.

See also
 List of islands of the Philippines

External links
Cagdanao Island Beach Resort official site

Category:Islands of Palawan
Category:Underwater diving sites in the Philippines


Gingerich

Gingerich is a surname. Notable people with the surname include:

 Edward Gingerich (1966–2011), Amish man convicted of manslaughter
 Mose Gingerich (born 1979), Amish-born documentary-maker
 Owen Gingerich (born 1930), American astronomer
 Philip D. Gingerich (born 1946), American paleontologist

See also
 2658 Gingerich, main-belt asteroid
 Gingrich, surname
 Giegerich, surname