What does : "The specifications ... of Pyxel are referring to ..PICO-8 and TIC-80." mean?
Does this mean it's api compatible with PICO-8? Or TIC-80? 

If not, why not, and if so, please state it plainly!

I'm new to this bit, and am trying to build games using a cross platform api that's simple, well supported, and has lots of examples.

Between PICO-8 and it's port to LOVE, 
https://github.com/picolove/picolove

I wonder what this brings to the table, with the direct comparison in your readme?

Thanks so much - not meaning this to sound negative in anyway, I'd just like to know!

Much appreciated ;-)

Brad